Results 101 to 110 of about 184,470 (336)
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi+8 more
wiley +1 more source
Marine Benthic Habitat Mapping of Muir Inlet, Glacier Bay National Park and Preserve, Alaska With an Evaluation of the Coastal and Marine Ecological Classification Standard III [PDF]
Seafloor geology and potential benthic habitats were mapped in Muir Inlet, Glacier Bay National Park and Preserve, Alaska, using multibeam sonar, ground-truth information, and geological interpretations. Muir Inlet is a recently deglaciated fjord that is
Cochrane, Guy R+4 more
core +2 more sources
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia+12 more
wiley +1 more source
Reproductive Den Habitat Characterization of American Badgers (\u3cem\u3eTaxidea taxus\u3c/em\u3e) in Central California [PDF]
The American badger (Taxidea taxus) is a species of special concern in California, and, as such, conservation measures are necessary. The goal of this study was to identify potential reproductive den habitat characteristics in order to more accurately ...
Huck, Katrina Louise
core +1 more source
Nanopriming enhances plant resilience to environmental challenges; however, its effectiveness across diverse genetic backgrounds, including genetic modifications and natural variations, remains uncertain. These findings demonstrate that nanopriming improves efficacy when natural genetic variations are considered, particularly in genetically modified ...
Yining Wu+4 more
wiley +1 more source
Nutrient and heavy metal composition in select biotic and abiotic components of Varthur wetlands, Bangalore, India [PDF]
T. V. Ramachandra+4 more
openalex +1 more source
The Potential for Abiotic Methane in Arctic Gas Hydrates [PDF]
Most methane enclosed in gas hydrates is biotic in origin, formed by microbial degradation of sedimentary organic matter. Increasingly, there is evidence that substantial gas hydrate may also be sourced from thermogenic decomposition of organic matter ...
Bunz, Stefan+3 more
core +1 more source
A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility
This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan+11 more
wiley +1 more source
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang+8 more
wiley +1 more source
Involvement of citrus shoots in response and tolerance to abiotic stress
Traditionally, the root system has been regarded as the primary component influencing citrus tolerance. Aerial tissues also play a crucial role in abiotic stress tolerance, as they are responsible for vital physiological processes, such as photosynthesis
Vicente Vives-Peris+3 more
doaj +1 more source