Results 41 to 50 of about 27,548 (334)

Visions d'Anna de Marie-Claire Blais: un voyage au coeur de l'abjection [PDF]

open access: yes, 2012
In the novel Visions d’Anna ou le vertige, by Marie-Claire Blais, the concept of abjection is essential and it highlights the hypocrisy and the complexity that characterizes social and family relationships.
Pich Ponce, Eva
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Borderline bodies [PDF]

open access: yes, 2002
This chapter is about borders that are made and broken at gay pride parades. Specifically, I examine the discursive and material borders maintained in tourism discourse.
Johnston, Lynda
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dispossession and Dislocation in J. M. Coetzee’s Age of Iron

open access: yesÉtudes Britanniques Contemporaines, 2017
Written during some of the darkest years of the apartheid regime, Age of Iron, Coetzee’s sixth novel, presents us with a radical experience of dispossession and destitution to which the main character and narrator subjects herself in response to the ...
Pascale Tollance
doaj   +1 more source

Designed to fail : a biopolitics of British Citizenship. [PDF]

open access: yes, 2004
Tracing a route through the recent 'ugly history' of British citizenship, this article advances two central claims. Firstly, British citizenship has been designed to fail specific groups and populations.
Imogen Tyler   +15 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The Marginality of the Gothic: A Reconsideration [PDF]

open access: yes, 2012
Viewing the Gothic as a notion shaped to a certain extent by the critic, this article investigates-and reconsiders-the persistence of the Gothic margin in contemporary critical discourse. Following Paul A.
Kliś Agnieszka
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

From Sensationalism to Sensation: Brian Evenson’s Affecting Texts

open access: yesTransatlantica, 2023
Brian Evenson’s work forcefully resists literary categorization, playfully mixing then deconstructing genres such as the Gothic, the western, post-apocalyptic fiction, magic realism to name but a few. Yet several short stories and novellas seem to strive
Nawelle Lechevalier-Bekadar
doaj   +1 more source

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