Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Can Intra-Operative Ablation-Specific Features Based on Ultrasound Fusion Imaging be Used to Predict Early Recurrence of Hepatocellular Carcinoma After Microwave Ablation: A Proof-of-Concept Study. [PDF]
Kang H+9 more
europepmc +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Marshall-Plan Ablation Strategy Versus Pulmonary Vein Isolation in Persistent AF: A Randomized Controlled Trial. [PDF]
Derval N+17 more
europepmc +1 more source
The Effects of Thermal Radiation, Conduction and Metoriod Heat Capacity on Meteoric Ablation [PDF]
J.C. Jones, Thomas Kaiser
openalex +1 more source
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
The efficacy of Netrod Six-electrode Radiofrequency Renal Denervation system: mathematical modeling, phantom experiments and animal studies. [PDF]
Song X, Guo J, Cao H, Nan Q.
europepmc +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Oxidation Resistance, Ablation Resistance, and Ablation Mechanism of HfC-B<sub>4</sub>C-Modified Carbon Fiber/Boron Phenolic Resin Ceramizable Composites. [PDF]
Wen H, Zhang W, Deng Z, Yang X, Huang W.
europepmc +1 more source