Results 271 to 280 of about 900,457 (343)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Real-world treatment patterns and outcomes in patients with early-stage HCC in the US treated with resection or ablation. [PDF]

Hepat Oncol
Parikh ND, Patel R, Hu J, Stirnadel-Farrant HA, Kebede N, Wang C, Garcia-Reyes K.   +6 more
europepmc   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Targeting the Substrate: Mechanism-Based Ablation Strategies for Persistent Atrial Fibrillation. [PDF]

J Clin Med
Marascu GE, Deaconu AI, Mitran RE, Stanciulescu LA, Vatasescu RG.   +4 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Catheter Ablation of Premature Ventricular Contractions from Right Ventricular Outflow Tract: Concept and Application of Very-High-Power, Very-Short-Duration as a First-Line Ablation Strategy. [PDF]

J Clin Med
Chen S, Ebrahimi R, Futyma P, Graeger S, Mirzayeva G, Neumann A, Schneppe D, Sartori LV, Janschel S, Kiuchi MG, Martinek M, Pürerfellner H.   +11 more
europepmc   +1 more source

Thermo-physics technical note No. 37: SNAP- 10A, Stainless Steel-316 vessel wall ablation. Final report

, 1964
Leslie D. Montgomery
openalex   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Impact of Ablation Targeting Atrial Drivers and Fragmented Potentials on Long-Standing Persistent Atrial Fibrillation: A Retrospective Study. [PDF]

J Arrhythm
Gibo Y, Ono M, Koyanagi Y, Yoshihiro K, Usumoto S, Gokan T, Okabe T, Isomura N, Muto M, Shiigai M, Honye J, Ochiai M.   +11 more
europepmc   +1 more source