Results 81 to 90 of about 3,742,547 (295)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Abnormality-aware multimodal learning for WSI classification

Frontiers in Medicine
Whole slide images (WSIs) play a vital role in cancer diagnosis and prognosis. However, their gigapixel resolution, lack of pixel-level annotations, and reliance on unimodal visual data present challenges for accurate and efficient computational analysis.
Thao M. Dang, Qifeng Zhou, Yuzhi Guo, Hehuan Ma, Saiyang Na, Thao Bich Dang, Jean Gao, Junzhou Huang   +7 more
doaj   +1 more source

Psikologi abnormal

, 2003
Judul asli : Abnormal psychology in a cahanging worldxv, 285 p.
greene, Beverly, Nevid, Jeffrey S.
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Indoor Abnormal Behavior Detection for the Elderly: A Review

Sensors
Due to the increased age of the global population, the proportion of the elderly population continues to rise. The safety of the elderly living alone is becoming an increasingly prominent area of concern.
Tianxiao Gu, Min Tang
doaj   +1 more source

Fault Detection and Diagnosis using Principal Component Analysis of Vibration Data from a Reciprocating Compressor [PDF]

, 2012
This paper investigates the use of time domain vibration features for detection and diagnosis of different faults from a multi stage reciprocating compressor.
Gu, Fengshou, Ball, Andrew, Ahmed, M.
core   +3 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Review of Multi-person Abnormal Behavior Detection Based on Deep Learning [PDF]

Jisuanji kexue yu tansuo
Content with the continuous advancement of deep learning technology, abnormal behavior detection has shifted from the traditional machine learning stage to the application of deep learning methods, and the research focus of abnormal behavior detection ...
WANG Yanjie, WANG Xiaoqiang, ZHAO Liurui, ZHUANG Xufei
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

VSM-UNet: A Visual State Space Reconstruction Network for Anomaly Detection of Catenary Support Components

Sensors
Anomaly detection of catenary support components (CSCs) is an important component in railway condition monitoring systems. However, because the abnormal features of CSCs loosening are not obvious, and the current CNN models and visual Transformer models ...
Shuai Xu, Jiyou Fei, Haonan Yang, Xing Zhao, Xiaodong Liu, Hua Li   +5 more
doaj   +1 more source