Results 211 to 220 of about 1,561,604 (300)

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu   +2 more
wiley   +1 more source

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

open access: yesEpilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez   +11 more
wiley   +1 more source

Water‐driven dispersible fiber electrode arrays for position‐dependent intracardiac electrophysiological recording

open access: yesFlexMat, EarlyView.
Abstract Intracardiac electrophysiological recording plays an essential role in identifying abnormal cardiac electrical activity and guiding arrhythmia diagnosis and treatment planning. A key challenge for minimally invasive intracardiac electrodes is to combine reliable transvascular delivery with stable and compliant endocardial contact.
Jinyang Mao   +7 more
wiley   +1 more source

Tail Risk Transmission in Agricultural and Energy Markets

open access: yesJournal of Futures Markets, EarlyView.
ABSTRACT This paper examines downside hedging, tail diversification, and extreme tail risk transmission between crude oil and agricultural commodity futures over two decades. We develop complementary indicators of downside dependence, including sign‐switching frequency and persistence, to assess tail risk dynamics, hedging effectiveness, and associated
Emmanuel Senyo Fianu   +3 more
wiley   +1 more source

State‐Dependent Market (In)Efficiency in Cryptocurrency Markets

open access: yesJournal of Futures Markets, EarlyView.
ABSTRACT This paper develops a meta‐learning framework to test whether cryptocurrency market inefficiency is static or state‐dependent. To resolve competing claims between the Efficient and Adaptive Market Hypotheses (AMH), we construct an adaptive trading strategy using high‐frequency data for 50 major cryptocurrencies.
Sasan Barak   +2 more
wiley   +1 more source

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