Results 61 to 70 of about 1,561,604 (300)

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao   +8 more
wiley   +1 more source

Analysis of Indonesian Capital Market Reaction to the Inauguration of the Indonesian Cabinet in 2024

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
The inauguration of the Indonesian Cabinet is considered one of the major political events that has the potential to influence the capital market. This study aims to analyze the reaction of the Indonesian capital market to the 2024 Cabinet Inauguration ...
Regita Putri Wardani   +3 more
doaj   +1 more source

Abnormal Accrual, Informed Trader, and Long-Term Stock Return: Evidence from Japan [PDF]

open access: yes
This study examines the association among abnormal accruals, long-term stock returns, and probability of informed trading. Some analytical and empirical research for postearnings announcement drift provide evidence that a high arrival rate of informed ...
Tomomi Takada   +2 more
core  

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

open access: yesAdvanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu   +8 more
wiley   +1 more source

THE IMPACT OF SHARES MOVING IN AND OUT OF FTSE/JSE TOP 40 INDEX

open access: yesJournal of Smart Economic Growth, 2020
This study explored the price reactions of shares moving in and out of Johannesburg Stock Exchange (JSE) Top 40 Index by applying three models to calculate the abnormal returns of the stocks; namely: the market model, the Capital Asset Pricing Model ...
Morotola Pholohane   +2 more
doaj  

Comparative Analysis of Abnormal Stock Returns Before and After Stock Split

open access: yes
The purpose of this study is to analyze whether there is a significant abnormal return before and after the stock split event and whether there is a difference in abnormal stock returns before and after the stock split event. The method used by researchers is quantitative method.
Ananda Naftalia, Wiwit Hariyanto
openaire   +2 more sources

Environmentally oriented energy policy and stock returns: an empirical analysis [PDF]

open access: yes
This paper analyzes the effect of environmental regulation on stock returns (as a measure of economic performance) for German energy corporations. By using event study methodology, we consider the last minute victory of the acting government in the 2002 ...
Ziegler, Andreas, Oberndorfer, Ulrich
core  

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

ANALISIS KOMPARATIF ABNORMAL RETURN SAHAM JII DAN NON JII SEBELUM DAN SESUDAH LIBUR IDUL FITRI (PERIODE 2009-2013)

open access: yesMIX: Jurnal Ilmiah Manajemen, 2016
: The purpose of this research is to examine differences between abnormal returns before and after Idul Fitri holidays on Jakarta Islamic Index stock (JII) compared with shares is not including the Jakarta Islamic Index stock (Non JII).
Hasanuddin Hasanuddin
doaj  

Brazilian Market Reaction to Equity Issue Announcements [PDF]

open access: yesBAR: Brazilian Administration Review, 2005
We have carried out an event study to investigate stock returns associated with the announcement of equity issues by Brazilian firms between 1992 and 2003 in order to determine market reaction before, during, and after the issue announcement.
Otavio Ribeiro de Medeiros   +1 more
doaj  

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