Results 11 to 20 of about 799,164 (305)

Prothrombotic coagulation abnormalities in patients with newly diagnosed multiple myeloma [PDF]

Haematologica, 2007
Prothrombotic coagulation abnormalities were analyzed in patients with untreated multiple myeloma. Increases in factor VIII, in von Willebrand factor and a decrease in protein S were observed and these changes were strongly associated with disease stage.
Johannes J.A. Auwerda, Pieter Sonneveld, Monica P.M. de Maat, Frank W.G. Leebeek   +3 more
doaj   +3 more sources

Rediscovering hemostasis abnormalities in multiple myeloma: The new era [PDF]

Heliyon
Multiple myeloma (MM) is a malignancy arisen from the abnormal proliferation of clonal plasma cells. It has a high risk of developing bleeding and thrombotic complications, which are related to poor prognosis and decreased survival.
Yudie Huang, Chongyu Wang, Hua Wang, Hong Liu, Lu Zhou   +4 more
doaj   +2 more sources

Eye Movement Abnormalities in Multiple Sclerosis: Pathogenesis, Modeling, and Treatment [PDF]

Frontiers in Neurology, 2018
Multiple sclerosis (MS) commonly causes eye movement abnormalities that may have a significant impact on patients’ disability. Inflammatory demyelinating lesions, especially occurring in the posterior fossa, result in a wide range of disorders, spanning ...
Alessandro Serra, Clara G. Chisari, Manuela Matta   +2 more
doaj   +2 more sources

Characterization of cytogenetic abnormalities in Lebanese multiple myeloma patients [PDF]

BMC Cancer
Background Multiple Myeloma (MM) is a hematological malignancy originating from the bone marrow and affecting the germinal lymphoid B cells, resulting in abnormal plasma cells and end organ damage.
Guitta Najem, Chloe Kharsa, Hampig Raphael Kourie, Joseph Kattan, Fadi Nasr, Fadi El Karak, Jad Wakim, Marwan Ghosn, Georges Chahine, Colette Hanna, Rachel El Ferkh, Chantal Farra, Alain Chebly   +12 more
doaj   +2 more sources

High‐risk cytogenetic abnormalities in multiple myeloma: PETHEMA‐GEM experience [PDF]

HemaSphere
This study examines the impact of cytogenetic abnormalities and their co‐segregation on the prognosis of newly diagnosed multiple myeloma patients. The analysis included 1304 patients from four different GEM‐PETHEMA clinical trials.
Veronica González‐Calle, Paula Rodriguez‐Otero, Maria J. Calasanz, Manuela Guijarro, Joaquin Martínez‐López, Laura Rosiñol, Miguel T. Hernández, Ana I. Teruel, Mercedes Gironella, Albert Oriol, Javier de laRubia, Ana P. González‐Rodríguez, Joan Bargay, Felipe deArriba, Luis Palomera, Marta‐Sonia González‐Pérez, Anna Sureda, Enrique Ocio, Juan J. Lahuerta, Joan Bladé, Jesus F. San Miguel, Maria V. Mateos, Norma C. Gutiérrez   +22 more
doaj   +2 more sources

Peripheral nervous system electrodiagnostic abnormalities in predominantly Hispanic Multiple Sclerosis patients [PDF]

, 2021
•The prevalence of electrodiagnostic abnormalities, especially axonal polyneuropathy, in the MS population may be higher than previously considered.•The presence of a peripheral axonal polyneuropathy may be important in the context of central axonopathy ...
Weinstock-Guttman, Bianca, Alexis A Lizarraga, Bianca Weinstock-Guttman, Rammohan, Kottil W, Sharma, Khema, Khema Sharma, Kottil W Rammohan, Lizarraga, Alexis A   +7 more
core   +1 more source

Data from: Multiple stressors and the cause of amphibian abnormalities [PDF]

, 2014
The repeated occurrence of abnormal amphibians in nature points to ecological imbalance, yet identifying causes of these abnormalities has proved complex.
Hagedorn, Birgit, Trust, Kimberly A., Rinella, Daniel, Battaglin, William, Holyoak, Marcel, Bogan, Daniel, Reeves, Mari K., Munk, LeeAnn, Dolph, Christine L., Perdue, Margaret   +9 more
core   +3 more sources

Una variación anatómica: la desembocadura aberrante del conducto torácico

Biomédica: revista del Instituto Nacional de Salud, 2009
En uno de los cadáveres disecados durante el primer semestre de 2006 en el anfiteatro del Departamento de Morfología de la Universidad del Valle en Cali (Colombia), se encontró una variación anatómica poco descrita en la literatura científica mundial. Se
Elizabeth Peña, Janneth Zuñiga
doaj   +1 more source

Amp(1q) and tetraploidy are commonly acquired chromosomal abnormalities in relapsed multiple myeloma. [PDF]

, 2023
Long-term disease control in multiple myeloma (MM) is typically an unmet medical need, and most patients experience multiple relapses. Fluorescence in situ hybridization (FISH) is the standard technique to detect chromosomal abnormalities (CAs), which ...
Jukic, Emina, Markus A. Keller, Eberhard Gunsilius, Schwendinger, Simon, Nachbaur, David, David Nachbaur, Willenbacher, Wolfgang, Steiner, Normann, Vogi, Verena, Teresa Kröll, Wolfgang Willenbacher, Mühlegger, Beatrix E, Oberhuber, Klaus, Keller, Markus A, Johannes Zschocke, Zschocke, Johannes, Martina Witsch‐Baumgartner, Maurus Locher, Kröll, Teresa, Gunsilius, Eberhard, Normann Steiner, Beatrix E. Mühlegger, Simon Schwendinger, Dominik Wolf, Emina Jukic, Witsch-Baumgartner, Martina, Klaus Oberhuber, Wolf, Dominik, Verena Vogi, Locher, Maurus, Irmgard Verdorfer, Verdorfer, Irmgard   +31 more
core   +1 more source

T2 lesion location really matters: a 10 year follow-up study in primary progressive multiple sclerosis [PDF]

, 2010
Objectives: Prediction of long term clinical outcome in patients with primary progressive multiple sclerosis (PPMS) using imaging has important clinical implications, but remains challenging.
Polman, C., Barkhof, F., Montalban, X, CHARD D, Thompson, A, Polman, C, F. Barkhof, Chard, D, Samson, R., D. Miller, Bodini, B., A. Thompson, Samson, R, MONTALBAN X, R. Samson, Rovira, A, POLMAN C, KHALEELI Z, O. Ciccarelli, Filippi, M., N. De Stefano, Barkhof, F, BATTAGLINI, MARCO, B. Bodini, A. Rovira, Battaglini, M, Polman, C.H., Chard, D., CICCARELLI O., Miller, D., Rovaris, M, Battaglini, M., Thompson, A., De Stefano, N., X. Montalban, MILLER D, ROVARIS M, FILIPPI M, D. Chard, Khaleeli, Z, SAMSON R, ROVIRA A, THOMPSON A, Rovaris, M., De Stefano, N, Rovira, A., Z. Khaleeli, Bodini, B, BODINI B, M. Filippi, Miller, D, BARKHOF F, DE STEFANO, NICOLA, M. Rovaris, Montalban, X., Ciccarelli, O., Ciccarelli, O, Khaleeli, Z., M. Battaglini, C. Polman, Filippi, M   +60 more
core   +1 more source