Results 51 to 60 of about 1,025,401 (190)

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

open access: yesTransfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman   +4 more
wiley   +1 more source

Development in Left Ventricular Mass After Early and Late Conversion From Calcineurin Inhibitors to Everolimus in Heart Transplant Recipients—Results From Two Randomized Controlled Trials

open access: yesClinical Transplantation, Volume 40, Issue 10, October 2026.
ABSTRACT Left ventricular hypertrophy in heart transplant recipients has been attributed to the use of calcineurin inhibitors. We assessed left ventricular mass across treatment arms in 83 heart transplant recipients in the Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE), and in 75 ...
Klaus Murbraech   +10 more
wiley   +1 more source

A case report of ABO-incompatible kidney transplant in human immunodeficiency virus-positive patient coinfected with both hepatitis B and hepatitis C viruses: A case report

open access: yesIndian Journal of Transplantation, 2022
Individuals with human immunodeficiency virus (HIV) are at increased risk for end-stage kidney disease (ESKD). Kidney transplantation is the best treatment for HIV-positive ESKD patients.
Raka Kaushal   +2 more
doaj   +1 more source

Early Morbidity and Survival After Left Lateral Segment Versus Whole Liver Graft Transplantation in Children

open access: yesPediatric Transplantation, Volume 30, Issue 10, October 2026.
Among 95 pediatric liver transplant recipients, LLS grafts carried greater early morbidity than whole liver grafts (CCI 53 vs. 45) but comparable graft and patient survival, supporting continued LLS use with an experienced surgical and medical team. ABSTRACT Background Left lateral segment (LLS) grafts expand graft availability for infants and small ...
Helena Linge   +12 more
wiley   +1 more source

Donor specific anti HLA sensitization is associated with inferior short term outcome in ABO- incompatible renal transplantation

open access: yesTransplantation Reports, 2020
Sixty six patients were evaluated for donor specific anti HLA sensitization before they received ABO incompatible kidney transplantation. Each recipient was evaluated by complement dependent cytotoxicity (CDC) crossmatch, flow cytometric crossmatch ...
Sonia Mehrotra   +6 more
doaj   +1 more source

Hyperacute rejection in ABO-incompatible kidney transplantation: Significance of isoagglutinin subclass

open access: yes, 2021
Introduction: ABO-incompatible transplantation has expanded the limited donor pool for kidney transplantation. Despite the successful desensitization protocols and immunosuppression, undesirable cases of hyperacute rejection occurs.
김영훈   +10 more
core   +1 more source

Innovative strategies in kidney paired donation: single-center experience achieving the highest annual transplant volume globally

open access: yesFrontiers in Immunology
BackgroundKidney Paired Donation (KPD) programs expand transplant opportunities for immunologically incompatible donor-recipient pairs. This study describes the operational framework and clinical outcomes of a high-volume, single-center KPD program ...
Khalid A. AlMeshari   +6 more
doaj   +1 more source

Thai Transplant Care Practice Guideline on Immunosuppressive Therapy for Adult Kidney Transplantation

open access: yesNephrology, Volume 31, Issue S2, September 2026.
ABSTRACT The Thai Transplantation Society developed these clinical practice guidelines to establish a comprehensive standard for immunosuppressive therapy in adult kidney transplantation. While rooted in evidence‐based medicine, the objective of this document extends beyond local application, serving as a practical model for low‐to‐middle‐income ...
Suwasin Udomkarnjananun   +12 more
wiley   +1 more source

An Approach to Antibody‐Mediated Rejection in Pediatric Liver Transplantation

open access: yesPediatric Transplantation, Volume 30, Issue 9, September 2026.
ABSTRACT Antibody‐mediated rejection (AMR) is an important but infrequent cause of pediatric liver allograft injury. There is a lack of standardized guidance, and treatment approaches vary across institutions. A writing group from the Society of Pediatric Liver Transplantation conducted a comprehensive review of the published literature and collected ...
Catalina Jaramillo   +8 more
wiley   +1 more source

Enzymatic conversion of blood group B kidney prevents hyperacute antibody-mediated injuries in ABO-incompatible transplantation

open access: yesNature Communications
Matching ABO blood group antigens between donors and recipients is critical to prevent hyperacute rejection in kidney transplantation. Enzymatic conversion of blood group antigens to the universal O type presents a promising strategy to overcome barriers
Jun Zeng   +14 more
doaj   +1 more source

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