Results 141 to 150 of about 75,128 (282)

Biological and clinical aspects of ABO blood group system

The Journal of Medical Investigation, 2008
The ABO blood group was discovered in 1900 by Austrian scientist, Karl Landsteiner. At present, the International Society of Blood Transfusion (ISBT) approves as 29 human blood group systems. The ABO blood group system consists of four antigens (A, B, O and AB). These antigens are known as oligosaccharide antigens, and widely expressed on the membranes
openaire   +3 more sources

The THOR network best practices for females of childbearing potential with life‐threatening hemorrhage: Guidance for emergency medical services and hospitals

Transfusion, EarlyView.
Matthew J. Levy, Holly OByrne, Eric A. Bank, Jeremy W. Cannon, Andew P. Cap, Elon Glassberg, John B. Holcomb, Donald H. Jenkins, Christine Leeper, Molly R. Sherwood, Kevin R. Ward, Mark H. Yazer, Philip C. Spinella   +12 more
wiley   +1 more source

Routine transfusion of Rh(D)‐positive RBCs to Rh(D)‐negative patients designated as do not resuscitate conserves Rh(D)‐negative red blood cell inventory

Transfusion, EarlyView.
Abstract Background A minority of blood donors are Rh(D)‐negative, and Rh(D)‐negative red blood cell (RBC) products are often overutilized. As such, Rh(D)‐negative RBCs may be difficult to maintain in blood bank inventory. Study Design and Methods We changed our blood bank laboratory policy to approve non‐alloimmunized Rh(D)‐negative patients to ...
Julie Katz Karp, Jovanna Everetts, Juliana Guarente, Angelica Vivero, Tiffany Bohr, Mary Harach   +5 more
wiley   +1 more source

Low titer group O whole blood inventory conservation: The effect of implementing group A whole blood at a simulated civilian trauma center

Transfusion, EarlyView.
Abstract Background Substituting group A whole blood (GAWB) might relieve some of the burden on the low titer group O whole blood (LTOWB) inventory. This simulation examined the effect of implementing GAWB at a large trauma hospital. Study Design and Methods A civilian trauma center with LTOWB and GAWB par levels set to 22 and 10 units, respectively ...
Emilie A. Jochumsen, Jennifer Gurney, Donald Jenkins, Jansen N. Seheult, Philip C. Spinella, Ulrik Sprogøe, Mark H. Yazer   +6 more
wiley   +1 more source

Cord blood red cell concentrates for preterm neonate transfusion: Insights from the multicenter BORN trial

Transfusion, EarlyView.
Abstract Background The BORN trial suggested that using cord blood‐red blood cells (CB‐RBCs) to transfuse severely preterm neonates significantly improves clinical outcomes compared to standard adult donor RBCs (A‐RBC). Study Design and Methods The study illustrates CB‐RBC concentrate production and inventory management across nine CB banks ...
Claudio Pellegrino, Patrizia Papacci, Carlo Dani, Francesco Cresi, Giulia Remaschi, Giulia Ansaldi, Carmen Giannantonio, Maria Francesca Campagnoli, Barbara Vania, Marco Fabbri, Roberta Penta de Vera d' Aragona, Anna Molisso, Enrico Beccastrini, Antonella Dragonetti, Tina Pasciuto, Sabrina Gabbriellini, Silvia Baroni, Francesca Serrao, Velia Purcaro, Genny Raffaeli, Stefania Villa, Daniele Prati, Isabella Mondello, Alessandra Falcone, Maria Letizia Patti, Tiziana Boggini, Paola Bergamaschi, Iolanda Mozzetta, Caterina Giovanna Valentini, Emanuela Locatelli, Roberto Albiani, Federico Genzano Besso, Giulia Vanina Cantone, Alessandra Coscia, Alfonso Trimarchi, Anita Capone, Stefano Ghirardello, Giovanni Vento, Luciana Teofili   +38 more
wiley   +1 more source

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

Transfusion, EarlyView.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza, Thamy Silva, Mateus Domentino, Marina Conrado, João Oliveira, Elyse Moritz, Akemi Chiba, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Langhi Dante, Carla Dinardo   +11 more
wiley   +1 more source

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Hold on to your units: Quality of red cell concentrates is only affected after multiple transient warming events

Transfusion, EarlyView.
Abstract Background Cryopreserved red cell concentrates (RCCs) glycerolized using a high glycerol (40%) method can be stored below −65°C for up to 30 years; however, units may be inadvertently warmed above −65°C due to freezer failures, human errors, or routine inventory management.
Jayme Kurach, Mackenzie Brandon‐Coatham, Nishaka William, Carly Olafson, Tracey R. Turner, Anika Tahsin Rahman, Behrouz Ehsani‐Moghaddam, Gwen Clarke, Jason P. Acker   +8 more
wiley   +1 more source

Bacterial proliferation is comparable in red blood cell concentrates stored in DEHT/PAGGSM and DEHP/SAGM containers

Vox Sanguinis, EarlyView.
Abstract Background and Objectives The European Union's ban on the use of di(2‐ethylhexyl) phthalate (DEHP) in medical devices will take effect in 2030. DEHP is a plasticizer in polyvinyl chloride blood bags that helps stabilize the red blood cell membrane during hypothermic red blood cell concentrate (RBCC) storage.
Sandra Ramirez‐Arcos, Yuntong Kou, Dilini Kumaran, Geraldine M. Walsh, Anita Howell, Chryslain Sumian, Stefan Reichenberg, Quentin Brebant, Ken McTaggart   +8 more
wiley   +1 more source

Addressing racial disparities in representation across blood, stem cell and organ and tissue donor pools

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu, Sylvia Okonofua, Farnaz Farahbakhsh, Rupal Hatkar, Lauren Sano, Margarita Conway, Marie‐Claire Kapesa, Manuel Escoto, Murdoch Leeies, Warren B. Fingrut   +9 more
wiley   +1 more source