Results 21 to 30 of about 19,039 (151)

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton   +4 more
wiley   +1 more source

Psychosocial aspects of early detection in type 1 diabetes: Language matters, decision making and support needs

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim The potential implementation of early type 1 diabetes (T1D) detection pathways, encompassing autoantibody screening and longitudinal monitoring, raises important psychosocial considerations for ethical, person‐centred care. This review summarises evidence on the psychosocial impact of early T1D detection, identifying key evidence gaps and ...
Maartje de Wit   +14 more
wiley   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

open access: yesHaemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini   +4 more
wiley   +1 more source

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich   +7 more
wiley   +1 more source

Association Between ABO Blood Group System and COVID-19 Severity. [PDF]

open access: yesAm J Clin Pathol, 2022
Bshaena AM   +5 more
europepmc   +1 more source

Self‐Care Experiences and Support Needs of Community‐Dwelling Older Adults With Multimorbidity: A Qualitative Study Informed by the Caring Life‐Course Theory

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore how community‐dwelling older adults with multimorbidity experience, enact and navigate daily self‐care using the Caring Life‐Course Theory to identify opportunities for strengthening self‐care and self‐management support. Design Qualitative descriptive study.
Michael T. Lawless   +7 more
wiley   +1 more source

Detection of a weaker subgroup of A in ABO blood group system. [PDF]

open access: yesAsian J Transfus Sci, 2022
Chopra G   +4 more
europepmc   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai   +7 more
wiley   +1 more source

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