Results 31 to 40 of about 9,720 (165)

Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues.

open access: yesJournal of the National Cancer Institute, 2002
Numerous experimental, epidemiologic, and clinical studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs), particularly the highly selective cyclooxygenase (COX)-2 inhibitors, have promise as anticancer agents. NSAIDs restore normal apoptosis
M. Thun, S. J. Henley, C. Patrono
semanticscholar   +1 more source

Traditional and Novel Herbal Drugs Emerging as Potent Novel Combinations for Managing Morbidities by Pharmacological and Mechanistic Studies [PDF]

open access: yes, 2018
Background: Herbal drugs are used in treatment of diseases since decades. Major contributing factor for their use is easy availability, less expensive and more belief of common population because of relatively less side effects compared to allopathic ...
Chanchal Kumar   +4 more
core   +2 more sources

The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations [PDF]

open access: yes, 2014
Ethnopharmacological relevance: The prevalence of diabetes is on a steady increase worldwide and it is now identified as one of the main threats to human health in the 21st century.
Abdel-Hassan   +761 more
core   +2 more sources

Multiple NSAID-Induced Hits Injure the Small Intestine: Underlying Mechanisms and Novel Strategies [PDF]

open access: yes, 2012
Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause serious gastrointestinal (GI) injury including jejunal/ileal mucosal ulceration, bleeding, and even perforation in susceptible patients.
Boelsterli, Urs A.   +2 more
core   +2 more sources

Evaluation of Anti-Ulcer Activity of ArisaemaLeschenaultii [PDF]

open access: yes, 2012
Ethanolic and Aqueous extract of ArisaemaLeschenaultii was evaluated for its Antiulcer activity against naproxen induced ulcer. Different extracts of blume of A.
M.K.Panigrahi, VInay Jain
core   +1 more source

Potential Strategies in the Prevention of Nonsteroidal Anti-inflammatory Drugs-Associated Adverse Effects in the Lower Gastrointestinal Tract

open access: yesGut and Liver, 2019
With the increasing use of nonsteroidal anti-inflammatory drugs (NSAIDs), the incidence of lower gastrointestinal (GI) complications is expected to increase.
Chuan-Guo Guo, W. Leung
semanticscholar   +1 more source

Nonsteroidal Anti-Inflammatory Drugs Prevent Vincristine-Dependent Cancer-Associated Fibroblasts Formation

open access: yesInternational Journal of Molecular Sciences, 2019
Vincristine is used in the clinical treatment of colon cancer, especially in patients diagnosed in the advanced phase of cancer development. Unfortunately, similar to other agents used during antitumor therapy, vincristine might induce chemoresistance ...
Marta E. Wawro   +3 more
semanticscholar   +1 more source

Aspirin and nonsteroidal anti‐inflammatory drug use and keratinocyte cancers: a large population‐based cohort study of skin cancer in Australia

open access: yesBritish Journal of Dermatology, 2019
Nonsteroidal anti‐inflammatory drugs (NSAIDs) have been postulated as chemopreventive agents for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), but findings from observational studies have been inconsistent, and clinical trial data are ...
N. Pandeya   +11 more
semanticscholar   +1 more source

Nonsteroidal, antiinflammatory drug-induced gastrointestinal injuries and related adverse reactions: Epidemiology, pathogenesis and management

open access: yesThe Saudi Journal of Gastroenterology, 2007
A large proportion of the population all over the world consumes acetylsalicylic acid (ASA: aspirin) or other nonsteroidal, antiinflammatory drugs (NSAIDs). This is associated with a considerable morbidity and mortality.
Al Mofleh Ibrahim, Al Rashed Rashed
doaj  

Nonsteroidal Anti-Inflammatory Drugs: A Potential Pharmacological Treatment for Intracranial Aneurysm

open access: yesCerebrovascular Diseases Extra, 2019
Background: Saccular intracranial aneurysms (IAs) are outpouchings of the vessel wall of intracranial arteries. Rupture of IAs results in subarachnoid hemorrhage which is associated with high morbidity and mortality.
Courtney Fisher, S. Demel
semanticscholar   +1 more source

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