Results 31 to 40 of about 23,388 (267)

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Functional Departmentalism and Nonjudicial Interpretation: Who Determines Constitutional Meaning? [PDF]

open access: yes, 2004
Johnsen examines the roles of nonjudicial entities--especially the Congress and the president--in the development of constitutional meaning. Although the other two branches are fearful of challenging judiciary supremacy, functional departmentalism may ...
Johnsen, Dawn E.
core   +3 more sources

FastCat: Autonomous Discovery of Multielement Layered Double Hydroxide Alloy Catalysts for Alkaline Oxygen Evolution Reaction

open access: yesAdvanced Intelligent Discovery, EarlyView.
A machine learning‐guided self‐driving laboratory screened over 500 nickel‐based layered double‐hydroxide catalysts for alkaline oxygen evolution. Out of the eight metals, the robot uncovered a quaternary Ni–Fe–Cr–Co catalysts requiring only 231 mV overpotential to reach 20 mA cm−2.
Nis Fisker‐Bødker   +3 more
wiley   +1 more source

A new model of gynecological and obstetrical pessary [PDF]

open access: yesГинекология, 2016
This article presents a new model of gynecological and obstetrical pessary for treatment of pelvic organ prolapse, elimination of symptoms of stress urinary incontinence, preventive care and treatment of cervical insufficiency and habitual abortion.
M G Schneiderman, A V Gorshkov
doaj  

Evaluation of Chromosomal Anomalies and Polymorphisms in Primer Infertility, Azospermia and Habitual Abortion Patient Groups

open access: yesVan Tıp Dergisi, 2019
INTRODUCTION: Infertility is defined as the inability to achieve pregnancy despite regular sexual intercourse for one year, although a couple with fertility does not use contraception.
Evren Gümüş
doaj   +1 more source

Youth activism in Poland: Perceptions, participation and diverging perspectives from young people and activists

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Recent years have seen a growing scholarly interest in youth activism (YA), a phenomenon often viewed as a positive development in response to declining civic and political engagement among young people. However, most of the research focuses on the activists themselves and gives less attention to how YA is perceived by the broader youth ...
Martyna Elerian   +2 more
wiley   +1 more source

The Role of Free Radicals and Antioxidant in Abortion [PDF]

open access: yes, 2013
BACKGROUND: Free radicals and antioxidant exist in balance under normal condition. In prooxidant condition, excessive free radicals can initiate a state of oxidative stress (OS) followed by capillary endothelial cell damage, a process involved in the ...
Rahardjo, T. M. (Theresia)   +1 more
core   +4 more sources

Early evolutionary history of the seed

open access: yesBiological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman   +2 more
wiley   +1 more source

Immunotherapy for recurrent miscarriage due to alloimmune reasons [PDF]

open access: yesГинекология, 2017
The article presents the current understanding of the pathogenetic mechanisms of habitual abortion realization of alloimmune genesis and proposed methods of immunotherapy. The mechanisms of the impact and effectiveness of various drugs and cell therapies.
V A Saribegova   +3 more
doaj  

Chromosomal rearrangements as the cause of habitual abortions [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2007
Introduction Habitual abortion is a spontaneous abortion occurring in three or more successive pregnancies with no intervening pregnancies. Chromosomal aberrations account for approximately 50% of fetal losses prior to 15 weeks. Objective The aim of this
Petrović Bojana   +2 more
doaj   +1 more source

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