Results 21 to 30 of about 6,513 (239)
Group A Streptococcus (GAS) causing puerperal sepsis is a leading cause of maternal mortality worldwide. Although rare, GAS infection is a relatively significant public health concern because of its propensity to evolve rapidly into septic shock ...
Stephanie C. Tardieu, Elizabeth Schmidt
doaj +1 more source
Emergency Medicine Simulation Scenario: First-Trimester “Septic” Abortion
This case scenario is used to demonstrate effective communication skills with an underage patient and her parents when evaluating a pregnancy-related complication, identify a gynecologic etiology of undifferentiated low abdominal pain in a reproductive ...
Jonathan Davis, Lauren Weinberger
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PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She +14 more
wiley +1 more source
Background and Aims Septic abortion remains a major cause of maternal morbidity and mortality in low‐ and middle‐income countries. This study aimed to determine the prevalence, antibiotic susceptibility profiles, and determinants of septic abortion among
Guled Bashir Gaboose +5 more
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OVARIAN ABSCESS RUPTURE AFTER OOCYTE RETRIEVAL IN A PATIENT WITH ENDOMETRIOMA: CASE REPORT
Introduction. Pelvic abscess rupture is a rare complication following in-vitro fertilization procedures. Case presentation. We describe an unusual case of ovarian abscess rupture following transvaginal oocyte retrieval in a 31-year-old female with a ...
Nikoleta G. TABAKOVA +4 more
doaj +1 more source
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen +12 more
wiley +1 more source
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu +9 more
wiley +1 more source
Septic abortion can lead to severe maternal morbidity and mortality. The management of septic abortion can be complicated by a history of radical trachelectomy and transabdominal cerclage placement.
Lisa A. McNamee, Sharon Amir, Kiger Lau
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We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source

