Results 21 to 30 of about 6,513 (239)

Group A Streptococcus Septic Shock after Surgical Abortion: A Case Report and Review of the Literature

open access: yesCase Reports in Obstetrics and Gynecology, 2017
Group A Streptococcus (GAS) causing puerperal sepsis is a leading cause of maternal mortality worldwide. Although rare, GAS infection is a relatively significant public health concern because of its propensity to evolve rapidly into septic shock ...
Stephanie C. Tardieu, Elizabeth Schmidt
doaj   +1 more source

Emergency Medicine Simulation Scenario: First-Trimester “Septic” Abortion

open access: yesMedEdPORTAL, 2011
This case scenario is used to demonstrate effective communication skills with an underage patient and her parents when evaluating a pregnancy-related complication, identify a gynecologic etiology of undifferentiated low abdominal pain in a reproductive ...
Jonathan Davis, Lauren Weinberger
doaj   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

Antibiotic Susceptibility Profiles and Determinants of Septic Abortion Among Women Admitted for Abortion Care in Ugandan Satellite Teaching Hospitals: A Two‐Center Cross‐Sectional Study

open access: yesHealth Science Reports
Background and Aims Septic abortion remains a major cause of maternal morbidity and mortality in low‐ and middle‐income countries. This study aimed to determine the prevalence, antibiotic susceptibility profiles, and determinants of septic abortion among
Guled Bashir Gaboose   +5 more
doaj   +1 more source

OVARIAN ABSCESS RUPTURE AFTER OOCYTE RETRIEVAL IN A PATIENT WITH ENDOMETRIOMA: CASE REPORT

open access: yesArchives of the Balkan Medical Union, 2021
Introduction. Pelvic abscess rupture is a rare complication following in-vitro fertilization procedures. Case presentation. We describe an unusual case of ovarian abscess rupture following transvaginal oocyte retrieval in a 31-year-old female with a ...
Nikoleta G. TABAKOVA   +4 more
doaj   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

open access: yesAdvanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen   +12 more
wiley   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

open access: yesAdvanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu   +9 more
wiley   +1 more source

Septic Abortion at 17 Weeks Gestation after Radical Trachelectomy and Transabdominal Cerclage: A Case Report

open access: yesReproductive Medicine
Septic abortion can lead to severe maternal morbidity and mortality. The management of septic abortion can be complicated by a history of radical trachelectomy and transabdominal cerclage placement.
Lisa A. McNamee, Sharon Amir, Kiger Lau
doaj   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

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