Results 221 to 230 of about 1,072,023 (350)

Downregulation of Chromosome 19 miRNA Cluster and the Tumor‐Suppressive Role of miR‐517a‐3p in Choriocarcinoma

open access: yesCancer Science, EarlyView.
Chromosome 19 microRNA cluster was downregulated in choriocarcinoma compared with complete hydatidiform mole. miR‐517a‐3p reduced the proliferation, migration, and invasion abilities of choriocarcinoma cell lines. Downregulation of SRSF1, targeted by miR‐517a‐3p, suppressed the malignant potential of choriocarcinoma cell lines. ABSTRACT Choriocarcinoma
Yuki Nishiko   +14 more
wiley   +1 more source

Prenatal Cell‐Free DNA Screening With Fetal Enrichment Enables Sampling From 8 Weeks of Gestational Age

open access: yesClinical Genetics, EarlyView.
Fetal fraction (FF) estimates for 170 male pregnancies sampled between 7w0d and 9w6d of GA as a function of gestational age at blood draw without (blue triangles) and with fetal enrichment (red dots). Regression lines are shown (gray 95% CI). Besides, there is a closer look at samples below 4% FF.
Seyedeh Saideh Daryabari   +6 more
wiley   +1 more source

Coronavirus Disease 2019 (COVID-19) Vaccination and Spontaneous Abortion. [PDF]

open access: yesObstet Gynecol
Sheth SS   +16 more
europepmc   +1 more source

Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations

open access: yesClinical Genetics, EarlyView.
Biallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Anees Muhammad   +11 more
wiley   +1 more source

Attune, animate and amplify: Creating youth voice assemblages in pARTicipatory sexuality education research

open access: yesChildren &Society, EarlyView.
Abstract This paper explores the politics and praxis of ‘youth voice assemblages’ in an exploratory and pARTicipatory research project where 125 young people (aged 11–18) from England, Scotland and Wales shared what and how they are learning about relationships, sex and sexuality.
EJ Renold   +5 more
wiley   +1 more source

Autophagy in PE: Dispute, Role and Potential Target

open access: yesCell Proliferation, EarlyView.
Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu   +12 more
wiley   +1 more source

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