Results 51 to 60 of about 49,409 (266)

Multiphase-based predictive framework construction of abrasive wear performance in C–V–Cr–Mo alloys

Journal of Materials Research and Technology
Abrasive wear persists as the dominant failure mechanism in crushing equipment, driving the demand for predictive models to guide wear-resistant alloy design and equipment lifespan assessment.
Tao Jiang, Xuke Yao, Mengmeng Ma, Hua Yu, Junjie Sun, Yuanguang Liu, Xuezhong Hu, Chong Chen, Chunhua Lei, Xiaodong Wang   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of aging temperature on microstructure and properties of maraging steel for ultra-low temperature

Journal of Materials Research and Technology
An 18Ni(200) maraging steel ingot was prepared using vacuum smelting, and after undergoing forging and two solution treatments at 1000 °C + 800 °C, the effect of aging treatment at 350–600 °C on the evolution of the microstructure and mechanical ...
Jikang Hu, Yucheng Zhou, Litao Yin, Haoqiang Zhang, Zhou Li, Liujie Xu   +5 more
doaj   +1 more source

Mass Distribution of Particulate Matter Produced During Abrasion af Asphalt Mixtures in Laboratory

Communications, 2016
Non-exhaust emissions of particulate matter from road traffic can come from abrasion of vehicle parts (tyres, brake linings, clutch and bodywork) or from pavement surface abrasion and also from resuspension of dust. A differentiation between PM emissions
Dasa Fullova, Daniela Durcanska, Dusan Jandacka, Adriana Estokova   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Investigation of the Friction and Wear Behavior of Cr-Mo-V Steel with Different Surface Treatment Processes

Lubricants
Hot work die steel is an alloy steel with good high-temperature performance, which is widely used in mechanical manufacturing, aerospace, and other fields.
Wei Zhang, Jian Zhang, Shizhong Wei, Liuliang Chen, Wei Zhang, Zhenhuan Sun, Chong Chen, Feng Mao, Xiaodong Wang, Caihong Dou, Cheng Zhang   +10 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Contribuição ao estudo da retificação abrasiva de materiais cerâmicos Introduction to abrasive grinding of ceramics

Cerâmica, 2006
Uma das principais limitações relacionadas ao processo de retificação de cerâmica é a confiabilidade do material devido aos defeitos introduzidos no processamento.
H. Fujita, E. C. Bianchi, P. R. de Aguiar, L. E. de A. Sanchez, C. E. da Silva Jr.   +4 more
doaj   +1 more source