Results 51 to 60 of about 49,247 (265)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Tribological Properties of 7A04 Aluminum Alloy Enhanced by Ceramic Coating

Lubricants
The 7A04 Al alloy is a commonly used lightweight metal material; however, its low wear resistance limits its application. In this study, the wear resistance of this alloy was improved by preparing micro-arc oxidation (MAO) coatings, MAO/MoS2 composite ...
Xiaobo Meng, Wei Zhang, Shizhong Wei, Kunming Pan, Xiaodong Wang, Tao Jiang, Xiran Wang, Changji Wang, Chong Chen, Feng Mao, Ziping Qiao, Jun Xue, Cheng Zhang   +12 more
doaj   +1 more source

Studying the Morphologic Maturation of Aeolian Sand Grains During Transportation Process of Wind Erosion (Case study: Khartouran Erg) [PDF]

Desert, 2009
Wind, in the duration of its erosional process, affects considerable changes in a grain's morphologyfrom its removal (detachment) step to sedimentation. In other word, a grain undergoes its gradualevolution during the transit process.
N. Mashhadi, M. Ekhtesasi
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Building a composition-microstructure-performance model for C–V–Cr–Mo wear-resistant steel via the thermodynamic calculations and machine learning synergy

Journal of Materials Research and Technology
To better understand the complex relationships between composition, microstructure, and performance in C–V–Cr–Mo wear-resistant steel, and to facilitate the rapid and efficient development of high-alloy steels for extreme working conditions, this study ...
Shuaiwu Tong, Shuaijun Zhang, Chong Chen, Tao Jiang, Peng Li, Shizhong Wei   +5 more
doaj   +1 more source

Investigation on Low Stress Scratching Abrasion Resistance Influencing Residual Stress in Nickel Chromium Alloyed Iron [PDF]

Archives of Foundry Engineering
In thermal power plants, advanced wear-resistant alloyed irons have been used for over three decades to enhance the longevity of parts. Ni-hard irons, high chromium irons, and HCHC materials are commonly used in components like liners, bull rig segments,
Sandeep Mashetty A., Sampathkumaran P., Ranjitha P., Chithirai Pon Selvan, Shridhar Deshpande C., Avinash Lakshmikanthan, Manjunath Patel G.C.   +6 more
doaj   +1 more source

Selection of an Optimal Abrasion Wheel Type for Nano-Coating Wear Studies under Wet or Dry Abrasion Conditions

Nanomaterials, 2020
Nanocoatings have numerous potential applications in the indoor environment, such as flooring finishes with increased scratch- and wear-resistance. However, given concerns about the potential environmental and human health effects of nanomaterials, it is
Li-Piin Sung, Yu-Fan Chung, David G. Goodwin, Elijah J. Petersen, Hsiang-Chun Hsueh, Paul Stutzman, Tinh Nguyen, Treye Thomas   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Review of Research on Hydraulic Mechanical Abrasion

Renmin Zhujiang, 2021
In the working process of hydraulic machinery,it is inevitable to suffer from the abrasion of fluid containing impurities.This paper introduces abrasion systematically and comprehensively from the following five aspects:the formation mechanism and ...
LI Xiaochao, XIE Weiwei, ZHANG Hao, QIN Rong, WANG Xiaoli   +4 more
doaj  

Improvement and In-Situ Application of an Evaluation Method of Ballasted-Track Condition Using Digital 2-D Image Analysis

Applied Sciences, 2020
The advancement in digital image analysis methods has led to the development of various techniques, i.e., quantification of ballast gravel abrasion. In this study, the recognition rate of gravel aggregates has been significantly increased by improving ...
Bongsik Park, Yeong-Tae Choi, Hyunmin Kim   +2 more
doaj   +1 more source