Results 51 to 60 of about 49,279 (266)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tribological Properties of 7A04 Aluminum Alloy Enhanced by Ceramic Coating

Lubricants
The 7A04 Al alloy is a commonly used lightweight metal material; however, its low wear resistance limits its application. In this study, the wear resistance of this alloy was improved by preparing micro-arc oxidation (MAO) coatings, MAO/MoS2 composite ...
Xiaobo Meng, Wei Zhang, Shizhong Wei, Kunming Pan, Xiaodong Wang, Tao Jiang, Xiran Wang, Changji Wang, Chong Chen, Feng Mao, Ziping Qiao, Jun Xue, Cheng Zhang   +12 more
doaj   +1 more source

Investigation on Low Stress Scratching Abrasion Resistance Influencing Residual Stress in Nickel Chromium Alloyed Iron [PDF]

Archives of Foundry Engineering
In thermal power plants, advanced wear-resistant alloyed irons have been used for over three decades to enhance the longevity of parts. Ni-hard irons, high chromium irons, and HCHC materials are commonly used in components like liners, bull rig segments,
Sandeep Mashetty A., Sampathkumaran P., Ranjitha P., Chithirai Pon Selvan, Shridhar Deshpande C., Avinash Lakshmikanthan, Manjunath Patel G.C.   +6 more
doaj   +1 more source

Selection of an Optimal Abrasion Wheel Type for Nano-Coating Wear Studies under Wet or Dry Abrasion Conditions

Nanomaterials, 2020
Nanocoatings have numerous potential applications in the indoor environment, such as flooring finishes with increased scratch- and wear-resistance. However, given concerns about the potential environmental and human health effects of nanomaterials, it is
Li-Piin Sung, Yu-Fan Chung, David G. Goodwin, Elijah J. Petersen, Hsiang-Chun Hsueh, Paul Stutzman, Tinh Nguyen, Treye Thomas   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Building a composition-microstructure-performance model for C–V–Cr–Mo wear-resistant steel via the thermodynamic calculations and machine learning synergy

Journal of Materials Research and Technology
To better understand the complex relationships between composition, microstructure, and performance in C–V–Cr–Mo wear-resistant steel, and to facilitate the rapid and efficient development of high-alloy steels for extreme working conditions, this study ...
Shuaiwu Tong, Shuaijun Zhang, Chong Chen, Tao Jiang, Peng Li, Shizhong Wei   +5 more
doaj   +1 more source

Improvement and In-Situ Application of an Evaluation Method of Ballasted-Track Condition Using Digital 2-D Image Analysis

Applied Sciences, 2020
The advancement in digital image analysis methods has led to the development of various techniques, i.e., quantification of ballast gravel abrasion. In this study, the recognition rate of gravel aggregates has been significantly increased by improving ...
Bongsik Park, Yeong-Tae Choi, Hyunmin Kim   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Review of Research on Hydraulic Mechanical Abrasion

Renmin Zhujiang, 2021
In the working process of hydraulic machinery,it is inevitable to suffer from the abrasion of fluid containing impurities.This paper introduces abrasion systematically and comprehensively from the following five aspects:the formation mechanism and ...
LI Xiaochao, XIE Weiwei, ZHANG Hao, QIN Rong, WANG Xiaoli   +4 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source