Results 81 to 90 of about 97,202 (285)

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

Some thoughts on neural network modelling of micro-abrasion-corrosion processes [PDF]

open access: yes, 2008
There is increasing interest in the interactions of microabrasion, involving small particles of less than 10 μm in size, with corrosion. This is because such interactions occur in many environments ranging from the offshore to health care sectors.
Rocha, L.A.   +3 more
core   +2 more sources

Influence of air-abrasion and subsequent heat treatment on bonding between zirconia framework material and indirect composites [PDF]

open access: yes, 2012
The purpose of this study was to evaluate the influence of air-abrasion and subsequent heat treatment on the shear bond strength of the bond between indirect composites and a zirconia material.
Okazaki, Masayuki   +4 more
core   +1 more source

Longitudinal Changes in Adiposity After a Youth Sport‐Related Knee Injury: Informing Posttraumatic Osteoarthritis Prevention

open access: yesArthritis Care &Research, EarlyView.
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale   +6 more
wiley   +1 more source

Glacial erosion and bedrock properties in NW Scotland : abrasion and plucking, hardness and joint spacing [PDF]

open access: yes, 2011
Subglacial erosion beneath glaciers occurs predominantly by abrasion and plucking, producing distinct erosional forms. The controls on the relative importance of abrasion vs. plucking are poorly understood.
Maarten Krabbendam   +3 more
core   +1 more source

A Novel Approach to Estimate the Transition Temperature via Dynamic Nanoindentation

open access: yesAdvanced Engineering Materials, EarlyView.
A new dynamic nanoindentation‐based method was developed that uses the stiffness ratio as an indicator of the elastic–plastic deformation contributions at different temperatures. The approach successfully identified transition temperatures in ferritic steel and distinguished them from continuously ductile austenitic steel.
Stefan Zeiler   +4 more
wiley   +1 more source

Anticorrosive Performance of Smart Epoxy Coatings With Poly(urea‐formaldehyde) Microcapsules Filled With 5‐Ethylidene‐2‐norbornene

open access: yesAdvanced Engineering Materials, EarlyView.
PUF/ENB microcapsules were synthesized based on a sequential factorial design and incorporated into an epoxy matrix. Their anticorrosive action, associated with the self‐healing mechanism, demonstrated that the addition of microcapsules to the coating improved anticorrosive performance compared to pure epoxy coatings, particularly when the encapsulate ...
Vandicleya Alves Moreira   +6 more
wiley   +1 more source

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