Results 71 to 80 of about 49,760 (266)

Wear of Hard Dental Tissues and Methods of its Evaluation

Česká Stomatologie a Praktické Zubní Lékařství, 2018
Background: In addition to tooth decay, that is the most common disease of hard dental tissues, the dentist often encounters with so-called noncarious lesions.
P. Holík, Y. Morozova
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Analisis Abrasi Terhadap Pergeseran Tepi Pantai Dengan Digital Shorline Analisis System (DSAS)

Teras Jurnal: Jurnal Teknik Sipil
Abstrak   Pantai Cahaya Negeri, Kecamatan Lemong Kabupaten Pesisir Barat mengalami abrasi signifikan, berdampak pada pergeseran tepi pantainya. Tujuan penelitian adalah untuk mengkaji, mengidentifikasi dampak pergeseran tepi pantai oleh abrasi periode ...
alim yulianto, Ahmad Zakaria, Dyah Indriana Kusumastuti   +2 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Tribological Behavior of Glycerol/Water-Based Magnetorheological Fluids in PMMA Point Contacts

Frontiers in Materials, 2019
Comprehension of the tribological behavior of magnetorheological fluids is crucial for many applications, in particular for those related with high quality surface finishing.
Wagner O. Rosa, Fernando Vereda, Juan de Vicente   +2 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Sillons d’usure interproximaux : reproduction expérimentale, analyse et application des résultats aux observations sur la lignée néandertalienne

Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2004
Siffre (1911) was the first to observe, on the left mandibular molars of the La Quina H5 Neandertal, a loss of dental tissues in “gutter” form located at the cemento-enamel junction.
Linda Bouchneb, Bruno Maureille
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source