Results 51 to 60 of about 50,291 (237)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Studying the Morphologic Maturation of Aeolian Sand Grains During Transportation Process of Wind Erosion (Case study: Khartouran Erg) [PDF]

Desert, 2009
Wind, in the duration of its erosional process, affects considerable changes in a grain's morphologyfrom its removal (detachment) step to sedimentation. In other word, a grain undergoes its gradualevolution during the transit process.
N. Mashhadi, M. Ekhtesasi
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Tribological Properties of 7A04 Aluminum Alloy Enhanced by Ceramic Coating

Lubricants
The 7A04 Al alloy is a commonly used lightweight metal material; however, its low wear resistance limits its application. In this study, the wear resistance of this alloy was improved by preparing micro-arc oxidation (MAO) coatings, MAO/MoS2 composite ...
Xiaobo Meng, Wei Zhang, Shizhong Wei, Kunming Pan, Xiaodong Wang, Tao Jiang, Xiran Wang, Changji Wang, Chong Chen, Feng Mao, Ziping Qiao, Jun Xue, Cheng Zhang   +12 more
doaj   +1 more source

Investigation on Low Stress Scratching Abrasion Resistance Influencing Residual Stress in Nickel Chromium Alloyed Iron [PDF]

Archives of Foundry Engineering
In thermal power plants, advanced wear-resistant alloyed irons have been used for over three decades to enhance the longevity of parts. Ni-hard irons, high chromium irons, and HCHC materials are commonly used in components like liners, bull rig segments,
Sandeep Mashetty A., Sampathkumaran P., Ranjitha P., Chithirai Pon Selvan, Shridhar Deshpande C., Avinash Lakshmikanthan, Manjunath Patel G.C.   +6 more
doaj   +1 more source

Selection of an Optimal Abrasion Wheel Type for Nano-Coating Wear Studies under Wet or Dry Abrasion Conditions

Nanomaterials, 2020
Nanocoatings have numerous potential applications in the indoor environment, such as flooring finishes with increased scratch- and wear-resistance. However, given concerns about the potential environmental and human health effects of nanomaterials, it is
Li-Piin Sung, Yu-Fan Chung, David G. Goodwin, Elijah J. Petersen, Hsiang-Chun Hsueh, Paul Stutzman, Tinh Nguyen, Treye Thomas   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Building a composition-microstructure-performance model for C–V–Cr–Mo wear-resistant steel via the thermodynamic calculations and machine learning synergy

Journal of Materials Research and Technology
To better understand the complex relationships between composition, microstructure, and performance in C–V–Cr–Mo wear-resistant steel, and to facilitate the rapid and efficient development of high-alloy steels for extreme working conditions, this study ...
Shuaiwu Tong, Shuaijun Zhang, Chong Chen, Tao Jiang, Peng Li, Shizhong Wei   +5 more
doaj   +1 more source

Improvement and In-Situ Application of an Evaluation Method of Ballasted-Track Condition Using Digital 2-D Image Analysis

Applied Sciences, 2020
The advancement in digital image analysis methods has led to the development of various techniques, i.e., quantification of ballast gravel abrasion. In this study, the recognition rate of gravel aggregates has been significantly increased by improving ...
Bongsik Park, Yeong-Tae Choi, Hyunmin Kim   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source