Results 151 to 160 of about 25,210 (289)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

Abrasive Water Jet Machining

open access: yes, 2015
Abrasive water jet machining (AWJM) is a relatively new machining technique. Abrasive Water Jet Machining is extensively used in many industrial applic ations. AWJM is a non- conventional machining process where material is removed by impa ct erosion of high pressure high velocity of water and entrained high velocity of grit abrasi ves on a work piece.
openaire   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

open access: yesAdvanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu   +13 more
wiley   +1 more source

Machining of Nitride Ceramics Using Elastic Tool with Discrete Cutting Profile

open access: yesМеханика машин, механизмов и материалов, 2009
The paper discusses distinctive features of machining of constructional nitride ceramics using fiber composites with various abrasive modifiers. The regressive models obtained reflect the dependence of metal removal on cutting speed and type of abrasive ...
L.V. Sudnik   +2 more
doaj  

Comparison of Flank Super Abrasive Machining vs. Flank Milling on Inconel® 718 Surfaces. [PDF]

open access: yesMaterials (Basel), 2018
González H   +4 more
europepmc   +1 more source

Effect of grinding on the fatigue life of titanium alloy (5 Al-2.5 Sn) under dry and wet conditions [PDF]

open access: yes
The principal factors in the performance of aerospace materials are strength-to-weight ratio, fatigue life, fracture toughness, survivability and, of course, reliability. Machining processes and, in particular, grinding under adverse conditions have been
Jeelani, Shaik   +2 more
core   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo   +14 more
wiley   +1 more source

Novel applications for TAZ-8A [PDF]

open access: yes
Recent needs in the non-aerospace industrial sector have revitalized interest in high performance alloys. TAZ-8A has a combination of properties that makes it unique: a high temperature strength, oxidation resistance, abrasion resistance, and exceptional
Riddlebaugh, Stephen M.   +1 more
core   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl   +27 more
wiley   +1 more source

Home - About - Disclaimer - Privacy