Results 41 to 50 of about 57,209 (299)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Serbian Civil Code in the history of Serbian law [PDF]
Pravni ZapisiThe Serbian Civil Code (SCC) of 1844, modelled after the Austrian General Civil Code (ABGB), was a reception of Austrian civil law in Serbia. While the SCC was in force the Serbian law was exposed to various foreign influences and subject to spontaneous ...
Popović Dragoljub
doaj +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Review on Regional Policies in the Law Number 23 of 2014 Concerning Regional Government and Related Laws and Regulations [PDF]
Košická bezpečnostná revueOne of the new points stipulated in Law Number 23 of 2014 Concerning Regional Government is the affirmation of regional rights to establish regional policies in carrying out government affairs that are within their jurisdiction, regional rights.
Bambang GIANTORO +2 more
doaj
The review of the right of adequate payment for the activities of the wife and the possibility of aggregating it with special property rights of divorce [PDF]
مطالعات زن و خانواده, 2018 During the process of legislation changes regarding work demands of the wife, the conditions for demanding adequate payment as well as the possibility of its aggregation or disaggregation with other financial rights of the wife which in particular arise ...
یوسف سبحانی +3 more
doaj +1 more source
Abrogation of Tolerance to Lens Proteins
Ophthalmic Research, 2009 Experimental lens induced granulomatous endophthalmitis has been induced in rats by employment of the allogeneic effect. This observation provides evidence that there is normally a state of T cell tolerance to lens proteins, while B cells are normally ...
George E. Marak, Jr. +2 more
openaire +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Analyze the Concept of “Insa” (Forgetfulness) and Critique the Interpreters’ Views [PDF]
آموزههای قرآنی, 2019 The discussion of “Insa” is mentioned in verse 106 of Baqarah. interpreters have proposed various views on the concept of Insa. Most of them, with their differences in meaning (abandonment, forgetfulness and delaying), allow “insa” in the verses of the ...
Marziyeh Fazli Nejad +2 more
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