Therapeutic Options for Childhood Absence Epilepsy
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years.
Victoria Elisa Rinaldi +3 more
doaj +3 more sources
Behavioral and Cognitive Comorbidities in Genetic Rat Models of Absence Epilepsy (Focusing on GAERS and WAG/Rij Rats) [PDF]
Absence epilepsy is a non-convulsive type of epilepsy characterized by the sudden loss of awareness. It is associated with thalamo-cortical impairment, which may cause neuropsychiatric and neurocognitive problems.
Evgenia Sitnikova
doaj +2 more sources
Huperzine A suppresses absence seizures in the genetic absence epilepsy rat from Strasbourg (GAERS) model of genetic generalized epilepsy with absence seizures [PDF]
Objective We evaluated huperzine A treatment in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) model of genetic generalized epilepsy (GGE) with absence seizures.
Pablo M. Casillas‐Espinosa +6 more
doaj +2 more sources
Dysfunction of the glymphatic system in childhood absence epilepsy [PDF]
Qiu Wenchao
exaly +2 more sources
The impact of early-life environment on absence epilepsy and neuropsychiatric comorbidities [PDF]
Gilles Van Luijtelaar +1 more
exaly +2 more sources
Rationale: Low-voltage-activated or T-type Ca2+ channels play a key role in the generation of seizures in absence epilepsy. We have described a homozygous, gain of function substitution mutation (R1584P) in the CaV3.2 T-type Ca2+ channel gene (Cacna1h ...
Pablo M. Casillas-Espinosa +8 more
doaj +1 more source
EEG phase synchronization during absence seizures
Absence seizures—generalized rhythmic spike-and-wave discharges (SWDs) are the defining property of childhood (CAE) and juvenile (JAE) absence epilepsies. Such seizures are the most compelling examples of pathological neuronal hypersynchrony.
Pawel Glaba +9 more
doaj +1 more source
Syndromic classification of patients with typical absence seizures [PDF]
The aim of this study is to compare ILAE classification (1989) and Panayiotopoulos' criteria (1997) for absence epilepsies. We studied 455 typical absences (ILAE, 1981) by video-EEG in 43 patients with normal neurological and neuroradiological ...
Laura M.F.F. Guilhoto +2 more
doaj +1 more source
Ethosuximide vs Valproate Long-term Remission of Absence Epilepsy
Investigators from the Epilepsy Center, Lurie Children's Hospital of Chicago, and Yale School of Medicine, New Haven, CT, examined the possible association between long-term seizure outcome of childhood absence epilepsy (CAE) and the initial treatment ...
J Gordon Millichap, John J Millichap
doaj +1 more source
Prognostic Factors for Absence Epilepsy in Childhood [PDF]
Purpose Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary.
So Young Kang +5 more
doaj +1 more source

