Results 91 to 100 of about 2,549,711 (355)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Age of the Tokkalehto metagabbro and its significance to the lithostratigraphy of the early Proterozoic Kuusamo supracrustal belt, northern Finland [PDF]
The c. 30-km2 Tokkalehto metagabbro and associated sills and dykes intrude a large part of the western part of the early Proterozoic Kuusamo supracrustal belt in northern Finland. These rocks have previously been mapped as a metavolcanic unit, Greenstone
P.M. Evins, K. Laajoki
doaj +1 more source
Red clump stars are fundamental distance indicators in astrophysics, although theoretical stellar models predict a dependence of absolute magnitudes with ages.
Aguirre, V. Silva +6 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The 3.5 Ga Siurua trondhjemite gneiss in the Archaean Pudasjärvi Granulite Belt, northern Finland [PDF]
In the Archaean Pudasjärvi Complex the pyroxene-bearing rocks are considered to form a belt, the Pudasjärvi Granulite Belt (PGB). The major rock types of the PGB are meta-igneous mafic and felsic granulites, and trondhjemite gneisses Red alaskites, white
T. Mutanen, H. Huhma
doaj +1 more source
Relative distances of Omega Centauri and 47 Tucanae
We present precise optical and near-infrared ground-based photometry of two Globular Clusters (GCs): Omega Cen and 47 Tuc. These photometric catalogs are unbiased in the Red Giant Branch (RGB) region close to the tip.
A. Calamida +42 more
core +1 more source
Prevalence of Metabolic Syndrome According to Absolute and Relative Values of Muscle Strength in Middle-Aged and Elderly Women [PDF]
Wangyang Zhang +3 more
openalex +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
[ABRIDGED] The LMC star cluster system offers the unique opportunity to independently check the accuracy of age and mass determinations based on a number of complementary techniques, including isochrone analysis.
Anders, Peter, de Grijs, Richard
core +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

