Results 91 to 100 of about 11,019,170 (342)
Racism and State Formation in the Age of Absolutism
Historical Materialism, 2023 Abstract This essay explores four questions through a critical dialogue with Black Marxist, Decolonial, and Political Marxist accounts of racism. First, is it possible to speak of racism before the advent of colonisation in the Americas? Second, what were the determinants for the production of these earlier modalities of racism? Third, who were the key
openaire +1 more source
Accurate brain age prediction with lightweight deep neural networks
bioRxiv, 2019 Deep learning has huge potential for accurate disease prediction with neuroimaging data, but the prediction performance is often limited by training-dataset size and computing memory requirements.
H. Peng +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The 3.5 Ga Siurua trondhjemite gneiss in the Archaean Pudasjärvi Granulite Belt, northern Finland [PDF]
Bulletin of the Geological Society of Finland, 2003 In the Archaean Pudasjärvi Complex the pyroxene-bearing rocks are considered to form a belt, the Pudasjärvi Granulite Belt (PGB). The major rock types of the PGB are meta-igneous mafic and felsic granulites, and trondhjemite gneisses Red alaskites, white
T. Mutanen, H. Huhma
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Additional evidence of the Holocene transgression in Lake Ladoga on the basis of an investigation of the beach deposits on the island of Mantsinsaari [PDF]
Bulletin of the Geological Society of Finland, 1995 On the basis of a study of peats covered by a beach ridge on the island of Mantsinsaari in Lake Ladoga, the beginning of the Ladoga transgression here was dated at 2980 ± 80 radiocarbon years B.P. Similar dates have been obtained from the southern shores
I. Delusin, J. Donner
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Age-related changes in reach-to-grasp movements with partial visual occlusion - Fig 5
, 2019 (A-H). Illustration of dependent variables in full-vision and visual occlusion conditions in each age group. Maximum transport velocity (MV) (A), maximum aperture (MA) (B), deceleration time (DT) (C), absolute time of maximum aperture (TMA) (D), relative
Preeyanuch Sittisupapong (7321217) +4 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source