Results 231 to 240 of about 15,696 (309)

Mediterranean marine sediment cores database: unlocking paleoclimatic signals for the last 20,000 years. [PDF]

Sci Data
Viganò A, Agnini C.
europepmc   +1 more source

Large rock avalanches in the region of Hydraotes Chaos and Tiu Valles: Absolute dating and evolutionary model

Lisa Molaro, Marco Emanuele Discenza, Minnillo Mariacarmela, G. Komatsu, Enrico Miccadei   +4 more
openalex   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Tracing 2500 years of human betaherpesvirus 6A and 6B diversity through ancient DNA. [PDF]

Sci Adv
Guellil M, van Dorp L, Saag L, Beneker O, Bonucci B, Sasso S, Saupe T, Solnik A, Kabral H, Allmäe R, Bates J, Dittmar JM, Ge XJ, Inskip S, Jonuks T, Karmanov VN, Khartanovich VI, Larmuseau MHD, Aneli S, Cessford C, Kriiska A, Mägi M, Malve M, De Winter N, Metspalu M, Pagani L, Robb JE, Kivisild T, Houldcroft CJ, Scheib CL, Tambets K.   +30 more
europepmc   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

Advanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro, Ronald Heisser, Maheera Bawa, Bastien Aymon, Sarah Wu, Annika Marschner, Sonika Kohli, Angel Bu, Laura Rosado, Martin Culpepper, Xuanhe Zhao, Ritu Raman   +11 more
wiley   +1 more source

Re-Os geochronology for sulfides and organic-rich sediments. [PDF]

Natl Sci Rev
Li Y, Glorie S, Selby D.
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Private Equity in Autism Services. [PDF]

JAMA Pediatr
Arnold DR, Reddy M, Cantor J, McBain RK, Yu H, Whaley CM, Singh Y.   +6 more
europepmc   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Comprehensive sampling of mitochondrial genomes substantiates the Neoproterozoic origin of land plants. [PDF]

Plant Commun
Hu SY, Shi G, Yang CA, Van de Peer Y, Li Z, Xue JY.   +5 more
europepmc   +1 more source