Results 31 to 40 of about 15,696 (309)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
RADIOCARBON DATING: PAST, PRESENT-DAY AND FUTURE - DEVELOPMENT OF I.P. GERASIMOV IDEAS
Бюллетень Почвенного института им. В.В. Докучаева, 2015 The ideas of I.P. Gerasimov on the radiocarbon soil age are outlined; the notions of absolute and relative soil age introduced by him are defined. Current trends in organic matter dating are discussed.
O. A. Chichagova, E. P. Zazovskaya
doaj +1 more source
Scientific Reports, 2021 Many works of art have been attributed to Leonardo da Vinci (1452–1519), the great artist-scientist-engineer of the Italian Renaissance; however, art historians have struggled to find definitive proof to connect Leonardo to these art pieces.
Ina Reiche, Lucile Beck, Ingrid Caffy
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Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Archeologické RozhledyThe historical town hall of Banská Bystrica was rebuilt in the second half of the 16th century from a medieval town mansion that had traditionally been owned by the town’s high-ranking citizens.
Martin Miňo +14 more
doaj +1 more source
Chronology of the Early and Middle Bronze Age in Hungary. New results [PDF]
Studia Hercynia, 2019 The chronological system established by Paul Reinecke played a significant role in developing a chronological classification of the Hungarian Bronze Age.
Viktória Kiss +5 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Rudarsko-geološko-naftni Zbornik, 2007 During the Great Zagreb's earthquake in 1880 consequences of the liquefaction have been detected at six sites in the vicinity of Zagreb as the occurrence of sand boils.
Želimir Veinović +2 more
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