Results 191 to 200 of about 499,871 (239)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The influence of keratometry on the accuracy of intraocular lens formulas in highly myopic eyes. [PDF]

BMC Ophthalmol
Li GY, Zhao P, Li ZY, Yang ZH, Li M, Xu J, Wan XH, Zhang JS.   +7 more
europepmc   +1 more source

Methionine Restriction Alone Induces T-cell-mediated Immunotherapy of Osteosarcoma in a Syngeneic Mouse Model. [PDF]

In Vivo
Mizuta K, Kubota Y, Aoki Y, Morinaga S, Asano Y, Miyashi Y, Bouvet M, Tome Y, Nishida K, Hoffman RM.   +9 more
europepmc   +1 more source

A Five-Year Comparative Effectiveness Analysis of Anterior Cervical Discectomy and Fusion Versus Cervical Total Disc Replacement: A Retrospective Multiparametric Evaluation of Clinical, Radiological, and Quality of Life Outcomes. [PDF]

Cureus
Dave BR, Agrawal SS, Vashishtha A, Krishnan A, Mayi SC, Rai RR, Dave MB, Panthackel M, Singh A, Kulkarni SS, Adodariya Y.   +10 more
europepmc   +1 more source

Effect of thermoformed tray architecture on transfer accuracy of lingual brackets: A prospective clinical study. [PDF]

PLoS One
Nguyen VA, Vuong TQT, Pham THT, Pham TT, Hoang V.   +4 more
europepmc   +1 more source

Reliability of a pressure pain threshold protocol: secondary analysis of a longitudinal trial with cluster randomization. [PDF]

PeerJ
Aguila-Humeres P, Leppe-Zamora J.
europepmc   +1 more source

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Least Absolute Deviations Curve-Fitting

SIAM Journal on Scientific and Statistical Computing, 1980
A method is proposed for least absolute deviation curve fitting. It may be used to obtain least absolute deviations fits of general linear regressions. As a special case it includes a minor variant of a method for fitting straight lines by least absolute deviations that was previously thought to possess no generalization.
Bloomfield, Peter, Steiger, William
openaire   +2 more sources