Results 51 to 60 of about 1,655,569 (337)

Tight Upper Bound Of The Maximum Speed Of Evolution Of A Quantum State [PDF]

open access: yes, 2010
I report a tight upper bound of the maximum speed of evolution from one quantum state $\rho$ to another $\rho'$ with fidelity $F(\rho,\rho')$ less than or equal to an arbitrary but fixed value under the action of a time-independent Hamiltonian. Since the
H. F. Chau, N. Margolus
core   +2 more sources

Analysis of least absolute deviation [PDF]

open access: yesBiometrika, 2008
SUMMARY We develop a unified L 1 -based analysis-of-variance-type method for testing linear hypotheses. Like the classical L2-based analysis of variance, the method is coordinate-free in the sense that it is invariant under any linear transformation of the covariates or regression parameters.
Chen, Kani   +3 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Laser frequency stabilization using a commercial wavelength meter

open access: yes, 2018
We present the characterization of a laser frequency stabilization scheme using a state-of-the-art wavelength meter based on solid Fizeau interferometers. For a frequency-doubled Ti-sapphire laser operated at 461 nm, an absolute Allan deviation below $10^
Chen, Peng   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sharp Bounds for the Deviation of a Function from the Chord Generated by its Extremities and Applications [PDF]

open access: yes, 2007
Sharp bounds for the deviation of a real-valued function f defined on a compact interval [a, b] to the chord generated by its end points (a, f (a)) and (b, f (b)) under various assumptions for f and f' including absolute continuity, convexity, bounded
Dragomir, Sever S
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Approaching Chemical Accuracy with Quantum Monte Carlo

open access: yes, 2012
A quantum Monte Carlo study of the atomization energies for the G2 set of molecules is presented. Basis size dependence of diffusion Monte Carlo atomization energies is studied with a single determinant Slater-Jastrow trial wavefunction formed from ...
C. J. Umrigar   +3 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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