Results 91 to 100 of about 1,323,926 (361)

A temporal network version of Watts's cascade model [PDF]

open access: yesIn: Holme, Saram\"aki, eds., Temporal Networks (Springer, Berlin, 2013), pp. 315-329, 2021
Threshold models of cascades in the social sciences and economics explain the spread of opinion and innovation due to social influence. In threshold cascade models, fads or innovations spread between agents as determined by their interactions with other agents and their personal threshold of resistance.
arxiv  

Threshold Choice Methods: the Missing Link [PDF]

open access: yes, 2011
Many performance metrics have been introduced for the evaluation of classification performance, with different origins and niches of application: accuracy, macro-accuracy, area under the ROC curve, the ROC convex hull, the absolute error, and the Brier ...
Ferri, Cèsar   +2 more
core  

Sharp Transition between Coalescence and Noncoalescence of Sessile Drops

open access: yes, 2014
Unexpectedly, under certain conditions, sessile drops from different but completely miscible liquids do not always coalesce instantaneously upon contact: the drop bodies remain separated in a temporary state of noncoalescence, connected through a thin ...
Karpitschka, Stefan, Riegler, Hans
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Simplified discrimination method and systematically threshold setting for pipe inspection using vibration-sensing-actuation device

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing
Water pipes have exceeded their service life, and the number of leakage and burst accidents is increasing. These accidents cause economic losses due to the interruption of operations and supply. However, replacing all the deteriorated pipes is difficult,
Naoko WATANABE, Soichiro TAKATA
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

The Impact of Prudence on Optimal Prevention Revisited [PDF]

open access: yes
This paper re-examines the link between absolute prudence and self-protection activities. We show that the level of effort chosen by a prudent agent is larger than the optimal effort chosen by a risk-neutral agent if and only if the degree of absolute ...
Georges Dionne, Jingyuan Li
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Hedging Errors Induced by Discrete Trading Under an Adaptive Trading Strategy [PDF]

open access: yesarXiv, 2010
Discrete time hedging in a complete diffusion market is considered. The hedge portfolio is rebalanced when the absolute difference between delta of the hedge portfolio and the derivative contract reaches a threshold level. The rate of convergence of the expected squared hedging error as the threshold level approaches zero is analyzed. The results hinge
arxiv  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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