Results 61 to 70 of about 3,367,707 (346)

TAPAS: A Thresholding Approach for Probability Map Automatic Segmentation in Multiple Sclerosis

open access: yesNeuroImage: Clinical, 2020
Total brain white matter lesion (WML) volume is the most widely established magnetic resonance imaging (MRI) outcome measure in studies of multiple sclerosis (MS).
Alessandra M. Valcarcel   +10 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Electron scattering in ethene: Excitation of the ã 3B1u state, elastic scattering, and vibrational excitation [PDF]

open access: yes, 2008
Experimental and calculated absolute differential cross sections for the scattering of low-energy electrons from ethene are presented. Emphasis is on the excitation of the ã 3B1u 3(pi,pi*) state, but selected elastic and vibrational excitation cross ...
Allan, M., McKoy, V., Winstead, C.
core  

Conditional generation of sub-Poissonian light from two-mode squeezed vacuum via balanced homodyne detection on idler mode [PDF]

open access: yes, 2001
A simple scheme for conditional generation of nonclassical light with sub-Poissonian photon-number statistics is proposed. The method utilizes entanglement of signal and idler modes in two-mode squeezed vacuum state generated in optical parametric ...
A. Luis   +26 more
core   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Does the impact of economic inequality on maternal and child health inequality exhibit a threshold effect? Evidence from China

open access: yesGlobal Public Health
When the economy (economic inequality) develops to a certain level, does the impact of economic inequality on health inequality change? Through threshold regression, this study analyses the impact of city-level economic inequality on the absolute and ...
Yao Yao, Yujie Cui, Wei Luan, Gordon Liu
doaj   +1 more source

Examining the Moral Threshold From the Perspective of Shahīd Moṭahharī with Emphasis on the Reality of Ethics [PDF]

open access: yesآموزه‌‌های فلسفه اسلامي
The moral threshold is regarded as the limit of true happiness. The aim of this research is to conclude this threshold from the statements of Shahīd Moṭahharī, considering the nature of moral reality through a descriptive-analytical method.
Ḥusayn Aḥmadī
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

TASTE SENSITIVITY CHANGES AMONG CONSUMERS OF PEMPEK-CUKO IN PALEMBANG CITY, SOUTH SUMATRA, INDONESIA [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences
Pempek is a typical food from Palembang, Indonesia. It is commonly consumed with cuko, a dipping sauce containing acetic acid which is corrosive. The research aimed to determine the absolute and recognition threshold, as well as changes in tongue ...
Budianto, Pratama F., Syafutri M.I.
doaj  

Reproducibility of Baseline Tumour Metabolic Volume Measurements in Diffuse Large B-Cell Lymphoma: Is There a Superior Method?

open access: yesMetabolites, 2021
The metabolic tumour volume (MTV) is an independent prognostic indicator in diffuse large B-cell lymphoma (DLBCL). However, its measurement is not standardised and is subject to wide variations depending on the method used.
Florian Eude   +5 more
doaj   +1 more source

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