Results 41 to 50 of about 2,701,014 (249)

Evaluation of otoacoustic emissions and brainstem auditory evoked potential in infants with birth asphyxia

open access: yesAsian Journal of Medical Sciences
Background: Recent technological evolutions allow for the identification of hearing level (HL) in infants soon after birth. The goal of early hearing detection and intervention is to maximize linguistic and communication skills and literacy development ...
Kavitha P   +3 more
doaj   +1 more source

Do uHear? Validation of uHear App for Preliminary Screening of Hearing Ability in Soundscape Studies [PDF]

open access: yesarXiv, 2022
Studies involving soundscape perception often exclude participants with hearing loss to prevent impaired perception from affecting experimental results. Participants are typically screened with pure tone audiometry, the "gold standard" for identifying and quantifying hearing loss at specific frequencies, and excluded if a study-dependent threshold is ...
arxiv  

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

open access: yesAdvanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang   +11 more
wiley   +1 more source

When Hearing Defers to Touch [PDF]

open access: yesarXiv, 2020
Hearing is often believed to be more sensitive than touch. This assertion is based on a comparison of sensitivities to weak stimuli. The respective stimuli, however, are not easily comparable since hearing is gauged using acoustic pressure and touch using skin displacement.
arxiv  

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

‘Lex Cryptographi(c)a,’ ‘Cloud Crypto Land’ or What? – Blockchain Technology on the Legal Hype Cycle

open access: yesThe Modern Law Review, Volume 86, Issue 1, Page 31-66, January 2023., 2023
Based on the reception of DLT/blockchain, this article argues that legal discourse is subject to hype cycle dynamics. Thinking in hype cycle categories provides a structured way for analysing the legal implications of a particular innovation. This critical engagement with enthusiasts, sceptics and pragmatists through the different stages may help to ...
Michael Anderson Schillig
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Test-retest reliability of remote home-based audiometry in differing ambient noise conditions

open access: yesFrontiers in Audiology and Otology
BackgroundHome-based remote audiometry has been emerging due to the increasing accessibility of mobile technology and the need for healthcare solutions that are available worldwide.
Iordanis Thoidis   +8 more
doaj   +1 more source

A ratchet mechanism for amplification in low-frequency mammalian hearing [PDF]

open access: yesProc. Natl. Acad. Sci. U.S.A. 107, 4973-4978 (2010), 2010
The sensitivity and frequency selectivity of hearing result from tuned amplification by an active process in the mechanoreceptive hair cells. In most vertebrates the active process stems from the active motility of hair bundles. The mammalian cochlea exhibits an additional form of mechanical activity termed electromotility: its outer hair cells (OHCs ...
arxiv   +1 more source

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