Results 51 to 60 of about 2,701,014 (249)

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Delirium‐associated medication in people at risk: A systematic update review, meta‐analyses, and GRADE‐profiles

open access: yesActa Psychiatrica Scandinavica, Volume 147, Issue 1, Page 16-42, January 2023., 2023
Abstract Background Drug‐associated delirium is a common but potentially preventable neuropsychiatric syndrome associated with detrimental outcomes. Empirical evidence for delirium‐associated medication is uncertain due to a lack of high‐quality studies.
Michael Reisinger   +4 more
wiley   +1 more source

Predicting the Perceptual Consequences of Hidden Hearing Loss

open access: yesTrends in Hearing, 2016
Recent physiological studies in several rodent species have revealed that permanent damage can occur to the auditory system after exposure to a noise that produces only a temporary shift in absolute thresholds.
Andrew J. Oxenham
doaj   +1 more source

Impact of controlling hypothyroidism on auditory dysfunction

open access: yesAl-Azhar Assiut Medical Journal, 2016
Background Hypothyroidism is defined as deficient thyroidal hormone production, and may be congenital or acquired. Aim The aim of the study was to determine the presence of auditory disorder in a group of Egyptian women with hypothyroidism and to detect ...
Naema Ismail   +3 more
doaj   +1 more source

DARF: A data-reduced FADE version for simulations of speech recognition thresholds with real hearing aids [PDF]

open access: yesarXiv, 2020
Developing and selecting hearing aids is a time consuming process which is simplified by using objective models. Previously, the framework for auditory discrimination experiments (FADE) accurately simulated benefits of hearing aid algorithms with root mean squared prediction errors below 3 dB. One FADE simulation requires several hours of (un)processed
arxiv  

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

open access: yesAdvanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini   +24 more
wiley   +1 more source

Effects of temperature on auditory sensitivity in eurythermal fishes: common carp Cyprinus carpio (Family Cyprinidae) versus Wels catfish Silurus glanis (family Siluridae).

open access: yesPLoS ONE, 2014
BackgroundIn ectothermal animals such as fish, -temperature affects physiological and metabolic processes. This includes sensory organs such as the auditory system.
Isabelle Pia Maiditsch, Friedrich Ladich
doaj   +1 more source

FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation

open access: yesAdvanced Science, EarlyView.
A new analytical pipeline, FREQuency‐resolved Network Estimation via Source Separation (FREQ‐NESS), reveals how the brain at rest is organized in frequency‐specific networks and dynamically rearranges during auditory stimulation. By analyzing source‐reconstructed magnetoencephalography (MEG) data, FREQ‐NESS uncovers the networks' prominence, spatial ...
Mattia Rosso   +6 more
wiley   +1 more source

Presenting Clinical Information on Rare Chromosome 6 Disorders via a Parent‐Centered Website: Parental and Professional Views

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The scarcity of clinical information surrounding rare chromosome disorders poses challenges for parents and clinicians. To bridge this gap for chromosome 6 disorders, the Chromosome 6 Project collects detailed genotype and phenotype data, aiming to provide aberration‐specific phenotype information to parents via an interactive website.
Eleana Rraku   +6 more
wiley   +1 more source

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