The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
A modified intrascleral intraocular lens fixation technique with fewer anterior segment manipulations: 27-gauge needle-guided procedure with built-in 8-0 absorbable sutures [PDF]
Yuan Yang +4 more
openalex +3 more sources
Ventriculoperitoneal Shunt without Hair Shaving Using Absorbable Suture Materials. [PDF]
Lee YH, Kwon YS, Cho JM.
europepmc +1 more source
Absorbable self-retaining barbed double-needle suture(SRBDS) in transperitoneal laparoscopic partial nephrectomy for T1 renal neoplasms [PDF]
Haibin Wei +8 more
openalex +1 more source
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
Tracheocutaneous fistula in patients undergoing supracricoid partial laryngectomy: the role of chronic aspiration [PDF]
The aim of the present retrospective controlled study was to analyse and compare risk factors for tracheocutaneous fistula in patients who received tracheostomy after supracricoid partial laryngectomy with those who received tracheostomy for other causes.
Calcagno, P +8 more
core
Evaluation of tensile strength of surgical synthetic absorbable suture materials: an in vitro study [PDF]
Sujeet V. Khiste +2 more
openalex +1 more source
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
A Suturing Method without Exposure of Barbs on the Wound Surface Using a Unidirectional Barbed Monofilament Absorbable Suture (STRATAFIX™) in Laparoscopic Myomectomy: A Feasibility Study. [PDF]
Ota Y +5 more
europepmc +1 more source
Performing a tarsorrhaphy. [PDF]
Tarsorrhaphy is the joining of part or all of the upper and lower eyelids so as to partially or completely close the eye. Temporary tarsorrhaphies are used to help the cornea heal or to protect the cornea during a short period of exposure or disease ...
Rajak, Juliette +2 more
core +2 more sources

