Results 41 to 50 of about 375,783 (265)

THE ULTRAVIOLET ABSORPTION SPECTRUM OF PEPSIN [PDF]

open access: yesJournal of General Physiology, 1934
The ultraviolet absorption spectrum of Northrop's pure crystalline pepsin has been determined. The curve of calculated molecular extinction coefficients is given. There is noted a general resemblance of the absorption curve for pepsin to that for urease and tyrosine; the absorption band is maximum at 2750–2800 Å.µ., minimum near 2500. A slight hump on
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pushing the Limit of Photo-Controlled Polymerization: Hyperchromic and Bathochromic Effects

open access: yesMolecules
The photocatalyst (PC) zinc tetraphenylporphyrin (ZnTPP) is highly efficient for photoinduced electron/energy transfer reversible addition-fragmentation chain transfer (PET-RAFT) polymerization. However, ZnTPP suffers from poor absorbance of orange light
Zhilei Wang   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tuned aggregation and film self-assembly of monomethincyanine dyes through variation of their monomer structure

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2019
Formation of condensed films and solution aggregates of four different monomethincyanine dyes have been studied using optical absorption spectroscopy and simulation methods, depending on variation of the dye monomer structure.
M.M. Sieryk
doaj   +1 more source

Design and Construction of Differential Optical Absorption Spectroscopy (DOAS) System for NOx Remote Sensing [PDF]

open access: yesEngineering and Technology Journal, 2016
Differential Optical Absorption Spectroscopy (DOAS) technique is one of the methods used for measurement, analysis and managing air pollution, studying the chemical properties of trace gases in the atmosphere, identification of critical (peak) values to ...
Mehdi M. Shellal   +2 more
doaj   +1 more source

Some Properties of Semiconductor-Ferroelectric Structures

open access: yesEast European Journal of Physics, 2023
This paper presents the properties of semiconductor-ferroelectric structures consisting of ZnO nanorods grown at low temperatures by the hydrothermal method on LiNbO3 and LiNbO3:Fe substrates.
Zakirjan T. Azamatov   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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