Results 81 to 90 of about 31,862 (304)

How Do IT Users’ Attributes Influence Innovative Use of IT: The Mediating Role of Individual Absorptive Capacity

open access: yesIEEE Access, 2019
Individual innovation is increasingly considered as a crucial element of organizational innovation. Prior research on user attributes as antecedents of innovation behavior (e.g., innovative use of IT) has identified three key factors: domain-specific ...
Yuan Sun   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Absorptive capacity in organizational theories: learning, innovation, managerial cognition [PDF]

open access: yesMarketing i Menedžment Innovacij, 2013
The paper studies an important issue of absorptive capacity that enables the companies to strengthen their position in the competitive global market.
O.A. Vasylieva
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Multinational Corporation and the Global Sourcing of Knowledge: Remodeling Absorptive Capacity [PDF]

open access: yes
We build on extant theory of the MNC, MNC subsidiaries, absorptive capacity and Penrose's concept of 'productive opportunity' to develop a framework on the MNC and absorptive capacity (AC) that allows us to explore the role of subsidiaries in the global ...
Papanastassiou, Marina   +3 more
core  

Absorptive capacity and smart companies

open access: yesIntangible Capital, 2014
Purpose: The current competitive environment is substantially modifying the organizations’ learning processes due to a global increase of available information allowing this to be transformed into knowledge.
Patricia Moro González   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Innovation in family businesses: Exploring the influence of entrepreneurial orientation and absorptive capacity on innovative capacity

open access: yesJournal of Innovation & Knowledge
Firms’ innovation positively affects their competitiveness and thus their financial performance. To bridge the research gap in the theoretical framework of dynamic capabilities and respond to the call for papers to explore new ways of analyzing ...
Felipe Hernández-Perlines   +2 more
doaj   +1 more source

Remarks about the research of the absorptive capacity construct

open access: yesIntangible Capital, 2007
The article tries to contribute to the literature on the absorptive capacity. More precisely, some limitations that have been found in the existing literature on the absorptive capacity, and some considerations for future research on the construct are ...
Vicenç Fernandez
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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