Results 111 to 120 of about 10,189,806 (382)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
LEKSIKON JAGUNG DALAM MASYARAKAT TUTUR JAWA
Retorika, 2018 : The formation of corn’s lexicons in Javanese. This study aims to describe the constituent elements and the type of reference from corn’s lexicons in Javanese. The type of this study is qualitative descriptive by using semantics theory approach. Methods
Fitri Febriyanti +1 more
doaj +1 more source
PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data
Database J. Biol. Databases Curation, 2019 Single-cell RNA sequencing is an increasingly used method to measure gene expression at the single cell level and build cell-type atlases of tissues. Hundreds of single-cell sequencing datasets have already been published. However, studies are frequently
Oscar Franzén, L. Gan, J. Björkegren
semanticscholar +1 more source
Polynomial functors and combinatorial Dyson-Schwinger equations
, 2017 We present a general abstract framework for combinatorial Dyson-Schwinger equations, in which combinatorial identities are lifted to explicit bijections of sets, and more generally equivalences of groupoids.
Bjorken J. D. +15 more
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Exclamative clauses at the syntax-semantics interface [PDF]
, 2013 Exclamative clauses exhibit a structural diversity which raises the question of whether they form a clause type in the sense of Sadock & Zwicky (1985).
Zanuttini, Raffaella
core
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
scMD facilitates cell type deconvolution using single-cell DNA methylation references
Communications BiologyThe proliferation of single-cell RNA-sequencing data has led to the widespread use of cellular deconvolution, aiding the extraction of cell-type-specific information from extensive bulk data.
Manqi Cai +3 more
doaj +1 more source
Non‐normal data: Is ANOVA still a valid option?
Psicothema, 2017 Background: The robustness of F‐test to non‐normality has been studied from the 1930s through to the present day. However, this extensive body of research has yielded contradictory results, there being evidence both for and against its robustness.
M. Blanca +4 more
semanticscholar +1 more source