Results 111 to 120 of about 8,751,229 (374)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Improving a data-acquisition software system with abstract data type components [PDF]

data types and object-oriented design are active research areas in computer science and software engineering. Much of the interest is aimed at new software development.
Howard, S. D.
core   +1 more source

Asynchronous data retrieval from an object-oriented database [PDF]

, 1988
We present an object-oriented semantic database model which, similar to other object-oriented systems, combines the virtues of four concepts: the functional data model, a property inheritance hierarchy, abstract data types and message-driven computation.
Bic, Lubomir, Gilbert, Jonathan P.
core  

Programming languages considered as abstract data types [PDF]

, 1980
J. Craig Cleaveland
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

DAS: a data management system for instrument tests and operations

, 2014
The Data Access System (DAS) is a metadata and data management software system, providing a reusable solution for the storage of data acquired both from telescopes and auxiliary data sources during the instrument development phases and operations.
Bulgarelli, Andrea, Cirami, Roberto, Conforti, Vito, Dadina, Mauro, Frailis, Marco, Franceschi, Enrico, Gianotti, Fulvio, Lodi, Marcello, Morbidelli, Roberto, Nicastro, Luciano, Pasian, Fabio, Sartor, Stefano, Smart, Ricky, Trifoglio, Massimo, Zacchei, Andrea, Zoli, Andrea   +15 more
core  

The application of machine learning techniques in posttraumatic stress disorder: a systematic review and meta-analysis

npj Digital Medicine
Posttraumatic stress disorder (PTSD) recently becomes one of the most important mental health concerns. However, no previous study has comprehensively reviewed the application of big data and machine learning (ML) techniques in PTSD. We found 873 studies
Jing Wang, Hui Ouyang, Runda Jiao, Suhui Cheng, Haiyan Zhang, Zhilei Shang, Yanpu Jia, Wenjie Yan, Lili Wu, Weizhi Liu   +9 more
doaj   +1 more source

UFL: An Experimental Frame Language Based on Abstract Data Types [PDF]

, 1986
S. Young
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

A quorum-consensus replication method for abstract data types [PDF]

, 1986
Maurice Herlihy
openalex   +1 more source