Results 141 to 150 of about 8,638,029 (373)

The cross talk between cancer‐associated fibroblasts and neutrophil extracellular traps in the tumor microenvironment

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The tumor microenvironment (TME) plays a pivotal role in tumorigenesis and metastasis, with cancer‐associated fibroblasts (CAFs) and neutrophil extracellular traps (NETs) identified as key contributors to its dynamic regulation. This review elucidates the multifaceted roles of CAFs and NETs in tumor progression and clarifies their intricate ...
Jiangbo Chen   +5 more
wiley   +1 more source

DRCTdb: disease-related cell type analysis to decode cell type effect and underlying regulatory mechanisms

open access: yesCommunications Biology
Understanding the molecular mechanisms underlying genetic diseases is challenging due to environmental and genetic factors. Genome-wide association studies (GWAS) have identified numerous genetic loci, but their functional implications are largely ...
Yunhui kong   +3 more
doaj   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

A Transactional Correctness Tool for Abstract Data Types

open access: yesACM Transactions on Architecture and Code Optimization (TACO), 2017
Christina L. Peterson, D. Dechev
semanticscholar   +1 more source

3D MRI Tract‐Specific Spinal Cord Lesion Pattern Improves Prediction of Distinct Neurological Recovery

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To distinguish lateralized motor‐ and sensory‐tract damage after acute spinal cord injury (SCI) and explore its predictive power for motor and sensory recovery. Methods Thirty‐five SCI patients (two female) from a multi‐center data set (placebo‐arm of the Nogo‐A‐Inhibition in SCI trial) underwent routine T2‐weighted sagittal MRI ...
Lynn Farner   +7 more
wiley   +1 more source

Some design constraints required for the assembly of software components: The incorporation of atomic abstract types into generically structured abstract types [PDF]

open access: yes
It is nearly axiomatic, that to take the greatest advantage of the useful features available in a development system, and to avoid the negative interactions of those features, requires the exercise of a design methodology which constrains their use.
Johnson, Charles S.
core   +1 more source

Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion   +15 more
wiley   +1 more source

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