Results 151 to 160 of about 8,638,029 (373)

Single-cell analysis of nasal epithelial cell development in domestic pigs

open access: yesVeterinary Research
The nasal mucosa forms a critical barrier against the invasion of respiratory pathogens. Composed of a heterogeneous assortment of cell types, the nasal mucosa relies on the unique characteristics and complex intercellular dynamics of these cells to ...
Wenqian Wang   +6 more
doaj   +1 more source

Influence of Dystrophin Isoform Deficiency on Motor Development in Duchenne Muscular Dystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increased central nervous system (CNS) involvement. We aimed to investigate how CNS involvement affects motor development in young DMD boys.
Mary Chesshyre   +152 more
wiley   +1 more source

HBI: a hierarchical Bayesian interaction model to estimate cell-type-specific methylation quantitative trait loci incorporating priors from cell-sorted bisulfite sequencing data

open access: yesGenome Biology
Methylation quantitative trait loci (meQTLs) quantify the effects of genetic variants on DNA methylation levels. However, most published studies utilize bulk methylation datasets composed of different cell types and limit our understanding of cell-type ...
Youshu Cheng   +14 more
doaj   +1 more source

The Diagnostic Value of Visual Evoked Potentials in Chronic Disorders of Consciousness

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In chronic disorders of consciousness (DOCs), the distinction between vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS) is as crucial as it is challenging. Evoked potentials (EPs) and event‐related potentials (ERPs) are helpful, but some limitations prevent their consistent use in the ...
Letizia Clementi   +14 more
wiley   +1 more source

Sceptic: pseudotime analysis for time-series single-cell sequencing and imaging data

open access: yesGenome Biology
Several computational methods have been developed to construct single-cell pseudotime embeddings for extracting the temporal order of transcriptional cell states from time-series scRNA-seq datasets.
Gang Li   +8 more
doaj   +1 more source

Mechanical Thrombectomy for TRACE‐III‐Eligible Patients With Ischemic Stroke: A Multicenter Retrospective Study Compared to TRACE‐III and TIMELESS Trials

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The results of the TRACE‐III trial demonstrated that tenecteplase (TNK) might be comparable to TNK combined with mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke within 4.5 to 24 h of onset, as tested in the TIMELESS trial.
Chongyang Huang   +13 more
wiley   +1 more source

Estimation of pore-type distribution utilizing petrophysical data and rock physics modeling on an Iranian carbonate reservoir

open access: yesJournal of Petroleum Exploration and Production Technology
Pore types in carbonate reservoirs are more complex than their sandstone counterparts due to the wide spectrum of their depositional environments and their more complicated post-depositional processes.
Ahadollah Mirshadi   +4 more
doaj   +1 more source

Poster : Blockchain abstract data type

open access: yes, 2019
This paper is the first to specify blockchains as a composition of abstract data types all together with a hierarchy of consistency criteria that formally characterizes the histories admissible for distributed programs that use them. The paper presents as well some results on implementability of the presented abstractions and a mapping of ...
Anceaume, Emmanuelle   +4 more
openaire   +1 more source

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