Results 21 to 30 of about 776,218 (307)

A novel gene selection method for gene expression data for the task of cancer type classification

open access: yesBiology Direct, 2021
Cancer is a poligenetic disease with each cancer type having a different mutation profile. Genomic data can be utilized to detect these profiles and to diagnose and differentiate cancer types. Variant calling provide mutation information. Gene expression
N. Özlem ÖZCAN ŞİMŞEK   +2 more
doaj   +1 more source

Spectral Properties of Some IRAS Starburst Galaxies at HI 21-cm statistic study [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
Many research deal with physical properties of HI gas in all types of galaxies.The 21cm data analysis allows to measure spectral and radio properties for galaxies, so it allows to study physical operation that assistant in starformation. We interest here
AKRAM M. Ali
doaj   +1 more source

MetaTiME integrates single-cell gene expression to characterize the meta-components of the tumor immune microenvironment

open access: yesNature Communications, 2023
Recent advances in single-cell RNA sequencing have shown heterogeneous cell types and gene expression states in the non-cancerous cells in tumors. The integration of multiple scRNA-seq datasets across tumors can indicate common cell types and states in ...
Yi Zhang   +14 more
doaj   +1 more source

SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data

open access: yesGenome Biology, 2019
Single-cell RNA-seq data contain a large proportion of zeros for expressed genes. Such dropout events present a fundamental challenge for various types of data analyses. Here, we describe the SCRABBLE algorithm to address this problem. SCRABBLE leverages
Tao Peng, Qin Zhu, Penghang Yin, Kai Tan
doaj   +1 more source

Search for malicious powershell scripts using syntax trees

open access: yesБезопасность информационных технологий, 2023
Purpose of the paper: a search for a rather abstract representation of the PowerShell script functionality using abstract syntax trees such that an invisible obfuscated PowerShell script can be detected provided the associated PowerShell script is ...
Viktor V. Erokhin
doaj   +1 more source

CoCoA-diff: counterfactual inference for single-cell gene expression analysis

open access: yesGenome Biology, 2021
Finding a causal gene is a fundamental problem in genomic medicine. We present a causal inference framework, CoCoA-diff, that prioritizes disease genes by adjusting confounders without prior knowledge of control variables in single-cell RNA-seq data.
Yongjin P. Park, Manolis Kellis
doaj   +1 more source

Machine learning-based analysis of cancer cell-derived vesicular proteins revealed significant tumor-specificity and predictive potential of extracellular vesicles for cell invasion and proliferation – A meta-analysis

open access: yesCell Communication and Signaling, 2023
Background Although interest in the role of extracellular vesicles (EV) in oncology is growing, not all potential aspects have been investigated. In this meta-analysis, data regarding (i) the EV proteome and (ii) the invasion and proliferation capacity ...
Matyas Bukva   +8 more
doaj   +1 more source

ScLSTM: single-cell type detection by siamese recurrent network and hierarchical clustering

open access: yesBMC Bioinformatics, 2023
Motivation Categorizing cells into distinct types can shed light on biological tissue functions and interactions, and uncover specific mechanisms under pathological conditions.
Hanjing Jiang   +3 more
doaj   +1 more source

A method for extracting travel patterns using data polishing

open access: yesJournal of Big Data, 2021
With recent developments in ICT, the interest in using large amounts of accumulated data for traffic policy planning has increased significantly. In recent years, data polishing has been proposed as a new method of big data analysis.
Mio Hosoe, Masashi Kuwano, Taku Moriyama
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

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