Results 51 to 60 of about 776,218 (307)

DTWscore: differential expression and cell clustering analysis for time-series single-cell RNA-seq data

BMC Bioinformatics, 2017
Background The development of single-cell RNA sequencing has enabled profound discoveries in biology, ranging from the dissection of the composition of complex tissues to the identification of novel cell types and dynamics in some specialized cellular ...
Zhuo Wang, Shuilin Jin, Guiyou Liu, Xiurui Zhang, Nan Wang, Deliang Wu, Yang Hu, Chiping Zhang, Qinghua Jiang, Li Xu, Yadong Wang   +10 more
doaj   +1 more source

PUREE: accurate pan-cancer tumor purity estimation from gene expression data

Communications Biology, 2023
Tumors are complex masses composed of malignant and non-malignant cells. Variation in tumor purity (proportion of cancer cells in a sample) can both confound integrative analysis and enable studies of tumor heterogeneity.
Egor Revkov, Tanmay Kulshrestha, Ken Wing-Kin Sung, Anders Jacobsen Skanderup   +3 more
doaj   +1 more source

Class-Diagrams for Abstract Data Types [PDF]

, 2017
We propose to extend iUML-B class-diagrams to elaborate Abstract Data Types (ADTs) specified using Event-B theories. Classes are linked to data types, while attributes and associations correspond to operators of the data types. Axioms about the data types and operators are specified as constraints on the class.
Hoang, Thai Son, Snook, Colin, Dghaym, Dana, Butler, Michael   +3 more
openaire   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Open Access GNSS Data for Studies of the Lithosphere

Geochemistry, Geophysics, Geosystems
Various types of Global Navigation Satellite System (GNSS) data are used for a wide range of applications. When modeled correctly, millimeter precision daily GNSS position time‐series yield velocities and other derived products that can be used for ...
D. Sarah Stamps, Corné Kreemer
doaj   +1 more source

A high spatial resolution dataset of China’s biomass resource potential

Scientific Data, 2023
Assessing biomass resource potential is essential for China’s ambitious goals of carbon neutrality, rural revitalization, and poverty eradication. To fill the data gap of high spatial resolution biomass resources in China, this study estimates the ...
Rui Wang, Wenjia Cai, Le Yu, Wei Li, Lei Zhu, Bowen Cao, Jin Li, Jianxiang Shen, Shihui Zhang, Yaoyu Nie, Can Wang   +10 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

A dataset that integrates Beach Litter, Beach Uses, and Coastal Oceanographic variables

Scientific Data
Marine litter is a multifaceted environmental issue requiring different data types for a better understanding of the problem. This paper presents a new dataset with approximately 6200 data records that compile different data types and sources focused on ...
Bruna De Ramos, Monica Ferreira da Costa
doaj   +1 more source