Results 181 to 190 of about 9,016 (226)

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +1 more source

What are patients' and healthcare professionals' views on managing penicillin allergy? A qualitative evidence synthesis. [PDF]

JAC Antimicrob Resist
Kildonaviciute K, Wanat M, Roberts NW, Sandoe J, Tonkin-Crine S.   +4 more
europepmc   +1 more source

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

Angewandte Chemie, EarlyView.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo, Kathleen Abt, Konrad Viehrig, Peter J. Jervis, Teresa P. Martins, Iñaki Lacomba, Chuhan Li, Daniele Castagnolo, Pedro N. Leão   +8 more
wiley   +1 more source

The use and methodological reporting of large language models in qualitative research: a scoping review. [PDF]

BMC Med Res Methodol
Kempny C, Frings J, Rust P, Meister S, Fehring L.   +4 more
europepmc   +1 more source

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

Angewandte Chemie, EarlyView.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando, Laora Boulo, Léonid Lavnevich, Elisa Teyssou, Stéphane Marot, Adélie Gothland, Jean‐Michel Guigner, Anne‐Geneviève Marcelin, Mickaël Ménand, Vincent Calvez, Matthieu Sollogoub   +10 more
wiley   +1 more source

Management strategies to mitigate burnout and turnover intention while enhancing patient safety in neonatal intensive care: an integrative review. [PDF]

Front Public Health
Huang X, Li Y, Hu Y, Li Y, Chen Q.
europepmc   +1 more source

From Root Cause Analysis to Systems Thinking: A Comparative Content Analysis of Patient Safety Incident Investigation Reports in Mental Healthcare. [PDF]

J Eval Clin Pract
Challinor A, Bhandari S, Bifarin O, Morasae EK, Xavier P, Saini P, Berzins K, Nathan R.   +7 more
europepmc   +1 more source

Depression as inferential rigidity: a meta-abductive account. [PDF]

Front Psychol
Sun J, Jin L.
europepmc   +1 more source