Results 231 to 240 of about 89,813 (307)

Defining Composition–Cytokine Relationships Enables the Design of Lipid Nanoparticles with Programmed Immunogenicity

open access: yesSmall, EarlyView.
Lipid nanoparticle composition governs distinct cytokine programs through the interplay of ionizable and polyethylene glycol‐conjugated (PEGylated) lipids. In vitro profiling, design of experiments (DoE) modeling, and in vivo validation reveal how formulation can tune reactogenicity‐associated pathways, while transgene expression remains the strongest ...
Adam Alexander Walters   +16 more
wiley   +1 more source

Local Structural Signatures of Shear Bands in Metallic Glasses via Electron Nanodiffraction

open access: yesSmall Methods, EarlyView.
In this research, we employed scanning electron nano‐diffraction to investigate the local degree of centrosymmetry and structural anisotropy (strain) in deformed metallic glass. The study provides significant new insights into the deformation mechanisms of glassy materials, revealing the nature of local structural transformations and demonstrating how ...
Huyen T. Pham   +6 more
wiley   +1 more source

Deformation and strength of grouted sleeve connectors in pre‐fabricated concrete structures: Mechanisms and analytical modeling

open access: yesStructural Concrete, EarlyView.
Abstract Grouted sleeve connectors (GSCs) are widely used in precast/prefabricated concrete structures. To ensure force transfer, connectors are often overdesigned in length. This practice has an unintended consequence of reducing the plastic deformation capacity of the connection region and hence the displacement ductility of the precast structure as ...
Hongning Ye, Yong Lu
wiley   +1 more source

Modelling the Four‐Dimensional Power Line Sag Dynamics by Point Signature in Time‐Series Synthetic‐Aperture Radar Images

open access: yesHigh Voltage, EarlyView.
ABSTRACT Power lines in synthetic‐aperture radar (SAR) images are reflected as point signatures, which fluctuate annually in both the azimuth and range directions. A novel framework is proposed in this paper to evaluate the four‐dimensional dynamic status of power line sag using those point signatures in time‐series SAR images.
Sijie Ma   +4 more
wiley   +1 more source

How much are you willing to pay to avoid lockdowns? Evidence from the real estate market

open access: yesReal Estate Economics, EarlyView.
Abstract In response to the COVID‐19 pandemic, numerous countries implemented lockdowns. In Victoria, Australia, a unique two‐tier system was employed, segregating areas with a Ring of Steel boundary and imposing additional restrictions within. This study focuses on the impact of lockdowns on housing prices and rents, exploring whether people are ...
Jian Liang, Chyi Lin Lee, Qiang Li
wiley   +1 more source

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