Results 111 to 120 of about 12,026,488 (347)

Do indexing and abstracting have a future? [PDF]

open access: yes, 2003
The World Wide Web presents information access problems orders of magnitude greater than any encountered before. These problems are identified and discussed.
Lancaster, F. Wilfrid, Lancaster, F. W.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

AUTOMATIC ABSTRACTING OF TEXTUAL MATERIAL

open access: yes, 2008
In what follows, we want to describe a system for the automatic abstracting of textual material. In designing the system, major theoretical questions have arisen not unlike those that arise in dealing with any natural language system.
Stephen L. Taylor   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Bases epistemológicas y operativas de la didáctica del resumen documental: un enfoque basado en la competencia resumidora

open access: yesPerspectivas em Ciência da Informação
Se destaca la necesidad de incluir una dimensión pedagógica dentro de las investigaciones de tratamiento documental de contenido, centrando la atención en el enfoque didáctico del resumen.
Mónica Izquierdo Alonso   +1 more
doaj   +1 more source

Knowledge, Practices, and Challenges of Library Practitioners on Abstracting

open access: yes, 2020
Access is the primary concern of a library thus information retrieval tool like an abstract is as important as the Online Public Access Catalog. Abstracting then plays an important role in improving access to information that is needed by library users ...
Jandoc, Judy Ann P.   +3 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Abstract abstracts and other abstractions [PDF]

open access: yesThe Journal of Wildlife Management, 2016
Paul R. Krausman   +2 more
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

indexing and abstracting. text processing

open access: yes, 2006
kuang-hua chen. department of library & information science. national taiwan university. indexing & abstracting. lecture 08 – text processing. 8-2. language & information processing system.
陳光華
core  

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