Results 71 to 80 of about 775,915 (321)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Graph Abstraction and Abstract Graph Transformation [PDF]

open access: yes, 2007
Many important systems like concurrent heap-manipulating programs, communication networks, or distributed algorithms are hard to verify due to their inherent dynamics and unboundedness.
Bauer, J.   +3 more
core   +1 more source

Imperfect-Recall Abstractions with Bounds in Games

open access: yes, 2016
Imperfect-recall abstraction has emerged as the leading paradigm for practical large-scale equilibrium computation in incomplete-information games. However, imperfect-recall abstractions are poorly understood, and only weak algorithm-specific guarantees ...
Kroer, Christian, Sandholm, Tuomas
core   +1 more source

Actors that Unify Threads and Events [PDF]

open access: yes, 2007
There is an impedance mismatch between message-passing concurrency and virtual machines, such as the JVM. VMs usually map their threads to heavyweight OS processes.
B. Chin   +14 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Construal Level Research in Decision Making: Analysis and Pushing Forward the Debate Using Bibliometric Review and Thematic Analysis

open access: yesAmerican Business Review, 2020
This study examines the extant literature on Construal Level Theory through bibliometric analysis that traces the path of research from 1998 to November 2019. It uses the Scopus database to identify emerging trends, seminal and most-cited papers, authors,
Arindra N. Mishra   +2 more
doaj   +1 more source

The Strength of Abstraction with Predicative Comprehension

open access: yes, 2015
Frege's theorem says that second-order Peano arithmetic is interpretable in Hume's Principle and full impredicative comprehension. Hume's Principle is one example of an abstraction principle, while another paradigmatic example is Basic Law V from Frege's
Walsh, Sean
core   +1 more source

Proton-transport catalysis, proton abstraction, and proton exchange in HF+HOC⁺ and H₂O+HOC⁺ and analogous deuterated reactions [PDF]

open access: yes, 2015
Classical simulations of the reactions of HF and H₂O with HOC⁺ have been carried out on interpolatedab initiopotential energy surfaces. Rearrangement (X+HOC⁺→OCH⁺+X), abstraction (X+HOC⁺→XH⁺+OC), (X=HF or H₂O), exchange (e.g., DY+HOC⁺→HY+DOC⁺), and ...
Collins, Michael A., Radom, Leo
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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