Results 91 to 100 of about 1,494,514 (261)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
University of Chitral Journal of Linguistics and Literature, 2023 This mixed-method, corpus-based study investigates across disciplinary variations in the abstracts of Pakistani dissertations spanning 16 disciplines in the light of Biber's multidimensional analysis approach. While prior research has explored variations
Nisa Fatima +2 more
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Index to NASA Tech Briefs, January - June 1967 [PDF]
, 1967 Technological innovations for January-June 1967, abstracts and subject ...
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Basic HPLC and CE of Biomolecules
Issues in Science and Technology Librarianship, 1999 Venkat Raman
doaj +1 more source
Global RheumatologyAbout Abstracts in Global Rheumatology We are pleased to announce that starting this year, Global Rheumatology will prominently feature abstracts as part of its designation as the official journal of the Pan-American League of Associations of ...
Global Rheumatology
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Alaskan water resources: Selected abstracts, 1974 [PDF]
, 1977 Compiled and Edited by Charles Hartman and Sheila. FinchAs one of the 51 Water Resources Research Institutes administered under the Water Resources Research Act of 1964, IWR receives a semimonthly journal entitled Selected Water Resources Abstracts.
Finch, Sheila, Hartman, Charles
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source