Results 71 to 80 of about 1,494,514 (261)

Design’s role on the [re]habilitation of social and urban structure [PDF]

, 2015
s aceptados sin presentacion / Accepted abstracts without ...
Miranda, Micael, Ribeiro, Adriano, Rivas, Manuel, Sampaio, Nelson   +3 more
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Using Machine Learning and Natural Language Processing to Review and Classify the Medical Literature on Cancer Susceptibility Genes

, 2019
PURPOSE: The medical literature relevant to germline genetics is growing exponentially. Clinicians need tools monitoring and prioritizing the literature to understand the clinical implications of the pathogenic genetic variants.
Acevedo, Francisco, Armengol, Victor Diego, Bao, Yujia, Barzilay, Regina, Braun, Danielle, Deng, Zhengyi, Hughes, Kevin S, Kim, Heeyoon, Ouardaoui, Nofal, Parmigiani, Giovanni, Wang, Cathy, Wang, Yan   +11 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Foundation to Promote Scholarship and Teaching 2012-2013 Awards [PDF]

, 2013
Proposal abstracts of 2012-2013 award recipients in a wide range of disciplinary ...
Office of the Provost, Roger Williams University
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A triclinic polymorph of bis(μ-N,N-bis(2-hydroxyethyl)dithiocarbamato-κ3S,S′:S′) bis(N,N-bis(2-hydroxyethyl)dithiocarbamato-κ2S:S′)zinc(II), C20H40N4O8S8Zn2

Zeitschrift für Kristallographie - New Crystal Structures, 2018
C20H40N4O8S8Zn2, triclinic, P1̄ (no. 2), a = 7.0675(10) Å, b = 9.9000(10) Å, c = 12.9252(17) Å, α = 106.813(10)°, β = 93.741(9)°, γ = 109.863(8)°, V = 800.65(18) Å3, Z = 2, Rgt(F) = 0.069, wRref(F2) = 0.176, T = 98(2) K.
Poplaukhin Pavel, Tiekink Edward R.T.
doaj   +1 more source

Neurofly 2008 abstracts : the 12th European Drosophila neurobiology conference 6-10 September 2008 Wuerzburg, Germany [PDF]

, 2009
This volume consists of a collection of conference ...
Buchner, Erich, Heisenberg, Martin
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source