Results 51 to 60 of about 522,925 (246)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The fate of adhering bacteria on antimicrobial surfaces: transcriptomic analysis of resistance associated genes and macrophage-mediated phagocytosis [PDF]

open access: yes, 2017
Book of Abstracts of CEB Annual Meeting 2017info:eu-repo/semantics ...
Alves, Diana Filipa Barros   +2 more
core  

Statistical evaluation of the function of the 1992 International Continence Society scientific committee [PDF]

open access: yes, 1994
Papers submitted to the International Confidence Society arc read by the six members of the scientific committee, who assign three scores to each paper, one for its originality, one for its scientific value, and one for its academic or clinical interest.
Downie, J.W. (J.)   +1 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Keratin peptides from chicken feathers for biomedical applications [PDF]

open access: yes, 2017
Book of Abstracts of CEB Annual Meeting 2017info:eu-repo/semantics ...
Botelho, C. M.   +2 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Room Temperature Ionic Liquid as Electrolyte for Lithium Ion Battery [PDF]

open access: yes, 2012
Symposium: Physical and Analytical Electrochemistry: no. I3, Molten Salts and Ionic Liquids 18published_or_final_version222nd Meeting of Electrochemical Society and Pacific Rim Meeting of Related Societies on Electrochemical and Solid-State Science ...
Fung, YS, Yang, Y
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Understanding the molecular basis behind hair morphology: development of new strategies to modulate hair from the follicle [PDF]

open access: yes, 2017
Book of Abstracts of CEB Annual Meeting 2017info:eu-repo/semantics ...
Cavaco-Paulo, Artur   +6 more
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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