Results 181 to 190 of about 1,832,592 (294)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Integrated Proteome and Phosphoproteome Profiling Reveals Abundance-Independent Phosphorylation Remodeling in Hepatocellular Carcinoma. [PDF]

Int J Mol Sci
Saleem S, Sajid MS, Varghese RS, Liu L, Muralidaran V, Kroemer A, Ressom HW.   +6 more
europepmc   +1 more source

Abundance and Meaning: What Abundance Exposes

Abstract: The meaning crisis attributed to post-scarcity conditions is not created by abundance but exposed by it. Public discourse frames automation-driven abundance as a transition problem: when labor ceases to be necessary, what replaces it? This framing presupposes labor-meaning was working — that it provided a valid ground for selfhood that must ...
openaire   +2 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Natural selection shapes the evolution of the metabolome in Saccharomyces cerevisiae. [PDF]

Mol Biol Evol
Li H, Liu H.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Do Flower-Rich Windbreak Margins Enhance Predator Communities in Citrus Orchards? [PDF]

Insects
Exilien R, Chuang A, Blaauw B, Knox G, Liesenfelt T, Strzyzewski I, Malfa K, Diepenbrock L, Martini X.   +8 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Analysis of 515 human proteomes defines plasma extracellular vesicle core composition, corona and coisolated networks. [PDF]

Commun Biol
Carvalho AS, Falcón-Pérez JM, Beck HC, Matthiesen R.   +3 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source